Viral Vector CDMO services
Product Description
MERCK
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FR -
2020On CPHI since
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4Certificates
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5000+Employees
Company types
Primary activities
Categories
MERCK
-
FR
-
2020On CPHI since
-
4Certificates
-
5000+Employees
Company types
Primary activities
More Products from MERCK (38)
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Product PBD Core™
Advanced intermediate.Enables rapid synthesis of PBD payloads.Suitable for up to phase I clinical studies with process, validation to support path to commercial approval.Contact one of our experts to request a free sample -
Product Pellicon® Capsules with Ultracel® Membrane
Accelerate your therapy using our innovative single-use tangential flow filters with superior flux performance. Ideal for single-use tangential flow filtration (TFF), Pellicon® Capsules provide high flux and linear scalability in a plug ‘n play format for optimum process flexibility and productivity. Pelli... -
Product ProCellics™ Raman Analyzer with Bio4C® PAT Raman Software
An Easy-to-Use GMP Process Analytical Technology (PAT) Platform to Monitor Cell Cultures In-Line and in Real-Time, from Process Development to Manufacturing -
Product Protein stabilizer portfolio
Specifically developed for high-risk applications, our portfolio of high-quality sugars, polyols, amino acids, and surfactants simplifies selection when you face critical challenges such as preventing aggregation during manufacturing. -
Product Small Molecule CDMO services
With Millipore® CTDMO Services we support small molecule API synthesis projects from milligram to commercial quantities. We are the partner to address the most difficult challenges, whether the target is difficult to handle, synthesize, or source. With a true consultative and partnered approach, our servic... -
Product Ultimus® Film
An innovative single-use film offering strength and leak resistance for your toughest liquid bioprocessing applications. Ultimus® film provides enhanced bag strength, improved durability and leak resistance through a novel strength layer reinforced by woven nylon. The inert fluid contact layer promotes hea... -
Product Viscosity Reduction Platform
The Viscosity Reduction Platform of proprietary excipient combinations enables subcutaneous formulation of highly concentrated protein biologics, bringing together increased concentrations and improved downstream processing. -
Product (R)-1,2-di-O-octadecenyl-3-trimethylammonium propane chloride
Cationic lipid used in the preparation of liposomes and lipoplexes. Specifically, R-DOTMA chloride with its positive charge allows the protective loading of nucleic acids into lipid nanoparticles and promotes their endosomal release. Merck as the solely manufacturer of DOTMA-Cl can provide you with high-pu... -
Product 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
Based on our unique lipid processing and isolation techniques Merck’s helper lipid DOPE demonstrates outstanding solubility and thus distinctive physico-chemical properties in comparison to conventional amorphous DOPE’s. Those improved handling properties facilitate your LNP formulation process -
Product ADC & Bioconjugation CDMO services
With 15+ years of contract development and manufacturing experience, Millipore® CTDMO Services offers leading expertise in the conjugation of drug linkers to monoclonal antibodies (mAbs). As ADC and Bioconjugation CDMO, we have comprehensive experience in conjugation technologies backed by broad analytical... -
Product API Processing portfolio
Choose API processing to improve API properties right from the start and avoid the risk of dealing with a poorly water-soluble API in formulation development or the need to start API development from scratch.
Whichever API processing method you decide to use, we pr... -
Product Benzonase® endonuclease portfolio
Benzonase® endonuclease is a unique, genetically engineered endonuclease that offers a variety of advantages over existing methods of nucleic acid removal. This enzyme has been designed to be supplied without protease activity and without the viral contaminants that can accompany enzymes isolated from ...
MERCK resources (36)
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News CPHI Pharma Awards 2023 – At the Heart of Pharma winners: Merck KGaA
After another year of impressive nominations for the CPHI Pharma Awards our winners were announced at CPHI Barcelona in October 2023. In this series of interviews, we speak to the people and teams behind the award-winning projects, concepts, and technologies. -
Brochure Millistak+® HC Pro fully synthetic depth filters for clarification and downstre
Millistak+® HC Pro (high-capacity synthetic media) is a family of synthetic depth filters -
News Which 10 drugs are open to price negotiation with Medicare in the USA?
The Centres for Medicare & Medicaid Services, under the Biden administration in the USA, has released a list of the 10 drugs that will be open to price negotiations as part of the new legislation under the Inflation Reduction Act (IRA). -
Brochure Novaseptum® SURe Sterile Sampling Assemblies
A single-use sterile sampling assembly that takes representative samples while protecting your bioprocess from cross-contamination. NovaSeptum® SURe sampling as -
News Pharma CEOs write open letter calling suppliers to commit to sustainability
Several big pharma companies have added their names to a letter challenging suppliers in the healthcare industry to pledge to sustainability targets. -
Brochure How to bring your LNP formulation to clinical/commercial manufacturing via CDMO
To enable the development of next-generation lipid-based drug delivery systems, expertise and manufacturing capabilities are critical. -
News Merck tests new formulation of Keytruda before the patent runs out
Merck tests new formulation of effective immunotherapy Keytruda to gain approval in time to extend the patent on the drug before it runs out in 2028. -
Technical Data Mobius® Breez Microbioreactor
A 2 mL Automated Perfusion Cell Culture Platform -
News Merck to donate new Ebola vaccine to defend against outbreaks in Uganda
Pharmaceutical giant Merck has announced they will be speeding up the processing of a new vaccine against the latest strain of the Ebola virus, to be donated to a global non-profit organisation for distribution -
Technical Data Millistak+® HC Pro fully synthetic depth filters for clarification and downstream filtration applications
Millistak+® HC Pro (high-capacity synthetic media) is a family of synthetic depth filters providing a cleaner and more consistent depth filtration media over current diatomaceous earth (DE) and cellulose (CE) based filter offerings. Multiple media grades are available for primary and secondary clarification as well as downstream filtration applications. -
Technical Data Natrix® Q Chromatography Membrane for single-use, scalable purification
Natrix® chromatography membrane is a high capacity, high throughput strong anion exchange device designed to purify biomolecules. It combines the capacity of high performing resins with the exceptional flow properties of chromatography membranes. The Natrix® chromatography membrane platform is fully scalable from 0.2 mL devices to production-scale and delivers enhancements in productivity, flexibility, and process robustness for any bioprocess. -
Technical Data Millistak+® Pod disposable depth filter system
Innovative, High-Performance Pod Filters are Ideal for Primary and Secondary Clarification in Lab, Pilot and Process-scale Applications. Millistak+® depth filter media is offered in a scalable, disposable format: the Pod Filter System. -
Technical Data Pellicon® Capsules with Ultracel® Membrane
Accelerate your therapy using our innovative single-use tangential flow filters with superior flux performance. -
Webinar MAST® Autosampling Solution
A Versatile & Modality-Agnostic Aseptic Autosampling Solution for Reliable On-Line and Near Real-Time Sample Analysis -
Technical Data ProCellics™ Raman Analyzer with Bio4C® PAT Raman Software
An Easy-to-Use GMP Process Analytical Technology (PAT) Platform to Monitor Cell Cultures In-Line and in Real-Time, from Process Development to Manufacturing. -
Technical Data Mobius iFlex® Bioreactor
The next generation of high performance single-use modular bioreactors for fed-batch and perfusion processes. The Mobius® iFlex Bioreactor is a scalable family of single-use bioreactors, ranging from 50 L to 2000 L and suitable for process development and commercial manufacturing. -
Technical Data Novaseptum® SURe Sterile Sampling Assemblies
A single-use sterile sampling assembly that takes representative samples while protecting your bioprocess from cross-contamination. NovaSeptum® SURe sampling assemblies can be easily integrated into your single-use manufacturing process. Available in five popular container formats and with two connection options. -
Technical Data Ultimus® Film
An innovative single-use film offering strength and leak resistance for your toughest liquid bioprocessing applications. Ultimus® film provides enhanced bag strength, improved durability and leak resistance through a novel strength layer reinforced by woven nylon. The inert fluid contact layer promotes healthy cell growth and is free of animal-origin components and Irgafos® 168. -
Technical Data Cellicon® Cell Retention Solution for Process Scale
Increase Your Bioreactor Productivity with Our Superior Solution for Upstream Process Intensification. In combination with your bioreactor, the Cellicon® Cell Retention Solution allows you to achieve significantly higher viable cell densities, improving your upstream productivity and manufacturing flexibility. -
Technical Data Cellicon® Perfusion Filter and Controller
A Superior Cell Retention Solution for N-1 Seed Train Intensification with Optimized Process Control. The benchtop Cellicon™ Perfusion Solution is designed to meet your perfused seed train challenges. It consists of a controller and a flat sheet cell retention filter with a single-use assembly running in tangential flow filtration mode. -
Technical Data Mobius® Gold High Cell Density Cryopreservation Assemblies (-80 °C)
A single-use assembly designed to facilitate the freeze and thaw of cryopreserved cells at -80 °C. Mobius® Gold High Cell Density Cryopreservation Assemblies enable seed train inoculation with cells at a higher cell density and larger volume, which significantly accelerates the cell expansion process. The single-use assembly also prevents contamination while improving process reproducibility. -
Webinar How to bring your LNP formulation to clinical/commercial manufacturing via CDMO services
To enable the development of next-generation lipid-based drug delivery systems, expertise and manufacturing capabilities are critical.Relying on more than 20 years experience in GMP lipid/LNP manufacturing, we aim at supporting pioneers in nucleic acid modalities to bring life changing medicines from preclinical to commercial manufacturing. -
Webinar Key Benefits of PCR-based mRNA manufacturing for clinical development
Learn more about the opportunities of the mRNA technology and how to overcome drug development and manufacturing challenges to bring your mRNA-based therapies to market in this series of webinars. -
Brochure Lipids for Pharmaceutical Applications
Your global partner for the manufacturing of synthetic lipids. Learn more about our offering of portfolio and customized lipids. -
Brochure Process Chemicals for RNA Drug Manufacturing
Providing high quality raw materials and services for mRNA manufacturing and formulation. -
Webinar SCALING FOR COMMERCIALIZATION: CONSIDERATIONS FOR LARGE-SCALE API PRODUCTION
As programs progress through the clinic stage and require scaling to larger-batch sizes, a seasoned commercial partner is critical for program success. Key considerations such as risk mitigation, production scalability, regulatory filing support, and specialized technological capabilities should be thoroughly evaluated. In this webinar, we take a look inside our latest capacity expansion for large-scale GMP API production located in Darmstadt, Germany. With a commitment to phase-appropriate quality, flexibility, and sustainability, the right CDMO partner can help navigate the complexities of large-scale programs. -
Video Industry largest capacity for highly potent APIs
State-of the-art facility for handling of HPAPIs in the single-digit nanogram OEL range. -
Video ADC Drug Development Acceleration Technologies
Discover our offering of ADC Express™ Services, ADCore advanced payload intermediates and ChetoSensar™ solubility enhancing technology. -
Brochure Small Molecule API and HPAPI Manufacturing Capabilities.
We support small molecule API synthesis projects from milligram to commercial quantities. We are the partner to address the most difficult challenges, whether the target is difficult to handle, synthesize, or source. -
Brochure DM-1
cGMP quality payload for your drug conjugate programs. -
Brochure ADCore payload intermdiates
Advanced intermediates -
Brochure Comprehensive ADC Services from pre-clinical to commercial
15 years of CDMO expertise in ADC and Bioconjugation with a broad experience in various conjugation technologies. -
Brochure Accelerate dissolution with Parteck(R) PLX 188 poloxamer.
Enhance dissolution rate and lubrication with a single high performance excipient.
Parteck® PLX provides consistent performance, improved dissolution rate and reliable lubrication – all at the same time.
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Webinar Strategies and Enabling Technologies for Enhancing API Solubility
Development of new active pharmaceutical ingredients (APIs) is lengthy and cost-intensive, thus avoiding any potential risk that may limit the product’s success is of utmost importance. Today, many APIs are not being commercialized as they are poorly water soluble and, as a result, exhibit too low bioavailability.PLX, MXP, SLC, Meglumine -
Whitepaper Poloxamer: A simple and powerful solution for accelerating dissolution
Absorption of molecules from the gastrointestinal tract is an essential consideration when developing orally delivered medications. Solubility, the concentration of drug in solution, is essential for this to occur and it is important to also consider the dissolution rate of the molecule. For DCS Class IIa molecules, defined as having a slow dissolution rate, simple yet effective formulations can be developed. Parteck® PLX 188 excipient should be considered for these challenging molecules to increase dissolution rate, provide hydrophilic lubrication, and enable simple and costeffective manufacturing processes. -
Whitepaper Poloxamer: A simple and powerful solution for accelerating dissolution
Absorption of molecules from the gastrointestinal tract is an essential consideration when developing orally delivered medications. Solubility, the concentration of drug in solution, is essential for this to occur and it is important to also consider the dissolution rate of the molecule. For DCS Class IIa molecules, defined as having a slow dissolution rate, simple yet effective formulations can be developed. Parteck® PLX 188 excipient should be considered for these challenging molecules to increase dissolution rate, provide hydrophilic lubrication, and enable simple and costeffective manufacturing processes.
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