3M™ Polisher ST can be used to replace downstream AEX polishing columns in both fed batch and continuous manufacturing. It features:
- 100x mAb loading of typical Q resin (10+ kg/m² target loading)
- Scalability from lab to manufacturing scale
- High salt and low pH tolerance
- Robust viral clearance across very wide range of conditions
This technology provides a compact, small footprint solution with higher capacity for delivering high purity and yield in the downstream polishing unit operation as part of a connected continuous downstream operation for the flexible facility of the future.
3M Polisher ST allows a facility strategy that can overcome scale limitations and enable cost-efficient manufacturing to support the growing demand for biologics.