Abbott & Enanta Report Positive Results from Hepatitis C Drug Study
Abbott and Enanta Pharmaceuticals have received positive results from a study for an investigational oral protease inhibitor being developed for the treatment of hepatitis C.
Abbott and Enanta Pharmaceuticals have received positive 12-week results from a Phase II study of ABT-450/r, an investigational oral protease inhibitor being developed for the treatment of hepatitis C.
The results revealed that 92% of the 24 patients receiving ABT-450/r once-daily, combined with standard of care, achieved complete early virologic response at 12 weeks.
In a separate analysis of three-day resistance data, ABT-450/r dosed at 200/100mg appeared to more consistently suppress the emergence of ABT-450-associated resistant variants than the 50/100mg and 100/100mg doses.
The 48-week Phase II study will evaluate the safety, tolerability, pharmacokinetic
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