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News
6 May 2021

ADL Pilot Plants: Scaling up your innovation to the next level

Pilot Plant

ADL has a broad know-how in the process development and scaling of new sustainable biotechnologies for multiple markets and industry sectors aimed at providing welfare to society (Food, Flavours and Fragances, Functional Molecules, Personal Care and others).

Our Pilot Plants for Fermentation (USP) and Recovery and Purification (DSP) have been specifically designed to enable the transition from lab to industrial scale, through fully tailored services and an extensive knowledge of bioprocess innovation.

Our customers will find in ADL the preferred partner that will lead them through an efficient operational process to take their biotechnology procedure from the lab to the commercial scale stage, in a feasible, sustainable way. With a fermentation scale-up capacity from 50 up to 225 m3 along with a fully dedicated DSP facility.

ADL Pilot Plants for USP and DSP are open-access facilities.
What does it mean?
1. They are open to the development of projects, from the starting development stages to the tailor-made production to any start-up, small and medium enterprise (SME), large enterprise or research organization.

2. We make available to customers ready to use and state-of-the-art large-scale infrastructure, as well as the associated expertise that guarantees a fast and effective scaling-up.

3. All this enable the translation of laboratory scale innovations into industrially viable processes.

4. The Project outline is designed to achieve the highest profit: Benefits of the open-access model:

  • Save time and money during the scaling-up process. 
  •  Shortening the time required for a new product or process to reach the market.
  •  Lowering the financial risks associated with scale-up.

5. This is done on a contractual basis. There is a commitment to keep a very close communication throughout the development of the project, thus ensuring an effective transfer of technology.  



FERMENTATION PILOT PLANT (USP)

This facility was completely refurbished in 2018 and has a total surface of about 1,000 SQM.

Here, we optimize, scale-up and transfer the fermentation protocol from our customers from the lab up to 2,000 L. At this site we have four main functional areas: media preparation, semi pilot laboratory, pilot plant and control room.

What we offer:

  • Process development and optimization. 
  •  Scale up of fermentation processes. 
  •  Batch and fed-batch aerobic fermentations. 
  •  Experience with bacteria, yeasts, filamentous fungi, and microalgae (heterotrophic). Authorized to work with BSL-1 & GMMs.


RECOVERY AND PURIFICATION (DSP) PILOT PLANT

In this plant, the main DSP processes used in the industry including, but not limited, to extraction, purification, and isolation, are available to be conducted after the fermentation process. Our equipment and our team of highly qualified engineers and technicians along with our know-how and decades of experience allowed us to develop and launch of wide variety of projects, involving multi-step and complex technology.


RECOVERY AND PURIFICATION (DSP) PILOT PLANT

In this plant, the main DSP processes used in the industry including, but not limited, to extraction, purification, and isolation, are available to be conducted after the fermentation process. Our equipment and our team of highly qualified engineers and technicians along with our know-how and decades of experience allowed us to develop and launch of wide variety of projects, involving multi-step and complex technology.

What we offer:

  • ATEX compliant installation.
  • DSP processes (separation, extraction, and purification).
  •  Chemical synthesis / conversion processes. 
  •  Process development and optimization. 

As part of our analytical services, ADL also has fully equipped Quality Control laboratories for all kind of GMP compliance analyses (chemical and microbiological).
Please, download the brochure included in our resources in order to know more about the reactors and auxiliary equipment, the analytical services and the capacities of our pilot DSP plant.
CERTIFICATIONS

GMP Food like monitoring of the processes (traceability, SOP, working protocols, etc.)
Authorized to work with BSL-1 & GMMs.
Experience in managing food grade, Halal and Kosher specifications.

Mentioned Companies
ADL BioPharma
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