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15 Feb 2012

AiCuris Announces Positive Results from Letermovir Trial

AiCuris has announced positive results from its placebo-controlled and dose-ranging trial with Letermovir (AIC246).

AiCuris GmbH &Co KG has announced positive results from its placebo-controlled and dose-ranging trial with Letermovir (AIC246).

 

In addition to excellent efficacy Letermovir demonstrates superior tolerability and safety and thus defines a novel standard for the control of HCMV in transplant patients.


 
133 HCMV-seropositive allogeneic human blood precursor cell (HBPC) recipients were included in the trial. Given orally for 84 days, the two dosages of Letermovir, 120 mg and 240 mg once daily, meet both primary efficacy endpoints with high statistical significance vs. placebo.

 

The efficacy endpoints are defined

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