Albumedix announces exclusive commercialization agreement with ThioLogics for its proprietary drug conjugation platform
Combining ThioLogics' site-specific conjugation chemistry with Albumedix's drug delivery platform enables the creation of next-generation albumin drug conjugates.
Albumedix has announced new data that supports an exclusive agreement with ThioLogics, a UCL Business (UCLB) company, to commercialize the next generation of stable albumin drug conjugates. The data demonstrates the serum stability advantages achieved by combining Albumedix's albumin-based drug delivery technology, Veltis, with ThioLogics' site-specific Next Generation Maleimide (NGM) chemistry platform, allowing significant improvements in cost of goods compared to conventional maleimide conjugation approaches.
Albumedix's agreement with ThioLogics unites its modified recombinant human albumin Veltis technology, with ThioLogics' site-specific NGM chemistry platform, to create serum stable albumin drug conjugates with enhanced pharmacokinetic and delivery capabilities. The new data indicates that the linking of the two platforms improves stability profiles in vivo for both natural and synthesized peptides and small molecules, with the potential for an enhanced safety profile and, therefore, increased patient compliance for drug products. In addition, the data reveals that no losses are observed during controlled hydrolysis when using the technology to produce albumin drug conjugates in vitro.
"Combining the benefits of Albumedix's and ThioLogics' technology platforms through this commercialization agreement allows us to jointly offer customers new capabilities to design stable and efficacious products across a broad-spectrum of drug candidates", said Dr Dave Mead, Business Development Director at Albumedix. "With an exclusive licensing agreement now in place, we look forward to working with our customers to show what can be achieved through this novel technology to link drugs to albumin."
“We are delighted to have formalized our exclusive marketing agreement with Albumedix, and to be making the promises of this combined technology platform a reality for our customers", commented Dr Chris Williams, Senior Business Manager at UCLB. "Together we have made it possible for manufacturers to harness the advantages of serum stable drug conjugates with tailored pharmacokinetics, helping to maximize the potential of novel drugs."
“Securing the Albumedix agreement is a major validation of Thiologics’ novel technology which has the potential to revolutionize the assembly of next generation biologics", said Cengiz Tarhan, Managing Director of UCLB.
Related News
-
News Patients vs Pharma – who will the Inflation Reduction Act affect the most?
The Inflation Reduction Act brought in by the Biden administration in 2022 aims to give better and more equitable access to healthcare in the USA. However, pharma companies are now concerned about the other potential costs of such legislation. -
News CPHI Podcast Series: What does the changing US Pharma market mean for industry and patients alike?
In this week's episode of the CPHI Podcast Series Lucy Chard, Digital Editor for CPHI Online is joined by James Manser to discuss the political and market changes in the US pharma field. -
News CPHI Barcelona Annual Report illuminates industry trends for 2024
The CPHI Annual Survey comes into it’s 7th year to report on the predicted trends for 2024. Over 250 pharma executives were asked 35 questions, with their answers informing the industry landscape for the next year, spanning all major pharma marke... -
News Which 10 drugs are open to price negotiation with Medicare in the USA?
The Centres for Medicare & Medicaid Services, under the Biden administration in the USA, has released a list of the 10 drugs that will be open to price negotiations as part of the new legislation under the Inflation Reduction Act (IRA). -
News EU Medical Devices Regulation causes unintended disappearances of medical devices for children, doctors state
Doctor groups and associations have appealed to the EU to correct the EU Medical Devices Regulation law that may cause unintended shortages of essential drug and medical devices for children and rare disease patients. -
News 10 Major Drug Approvals So Far in 2023
Last year, 37 novel drugs were approved by the FDA, this was a high number for such a category, and covered many fields including oncology, demonstrating how promising further research is, and how it is only continuing to build. To date, there are alre... -
News Detecting Alzheimer's disease with a simple lateral flow test
A novel rapid diagnostic test for early-stage Alzheimer's disease has been developed using a biomarker binder from Aptamer Group along with technology from Neuro-Bio, the neurodegenerative disease experts. -
News CPHI Podcast Series: outsourcing and manufacturing trends
Listen to the CPHI Podcast Series this June to hear Gil Roth of the PBOA speak with Digital Editor Lucy Chard about the biggest trends and topics to watch in pharma outsourcing and manufacturing at the minute.
Position your company at the heart of the global Pharma industry with a CPHI Online membership
-
Your products and solutions visible to thousands of visitors within the largest Pharma marketplace
-
Generate high-quality, engaged leads for your business, all year round
-
Promote your business as the industry’s thought-leader by hosting your reports, brochures and videos within your profile
-
Your company’s profile boosted at all participating CPHI events
-
An easy-to-use platform with a detailed dashboard showing your leads and performance