Alfasigma increases liquid injectable vial capacity in its sterile department at Alanno plant

Italian pharma company Alfasigma has increased its capacity for the production of liquid injectable vials in its sterile department of excellence at the Alanno manufacturing plant

The sterile department boasts a cutting-edge, high-speed and fully automatic IMA filling line with a productivity of 18,000 pcs/h, capable of filling aseptic liquid vials.

The high containment segregated line can handle small filling volumes of up to 100 ml, allows for management of the track and trace on the primary packaging, and performs continuous and 100% weight checks.

Fully integrated sterilization systems (ovens, autoclaves, passboxes) ensure the safety of the aseptic area in the line, according to top-quality standard requirements.

All equipment is connected to a validated computer system in order to guarantee the complete traceability and integrity of the data.

Given its advanced technical characteristics, the new line is particularly suitable for supporting production processes requiring outstanding reliability for the manufacturing of high-value products such as biotechnology compounds, biosimilars, and vaccines.

The sterile department is part of an overall 450 sqm expansion at Alanno, which also includes a department entirely dedicated to the production of pre-filled syringes, cartridges, and ready-to-use vials.

Alfasigma is a privately owned, Italy-based integrated multinational pharmaceutical company with revenues in excess of €1 billion, six manufacturing plants, R&D facilities, and 3,000 employees globally. Outside of its core Italian market, Alfasigma has 19 subsidiaries in Europe, Asia, North and Central America, and Africa, and is present in more than 90 countries.

The Alanno plant processes rifaximin, a molecule for the treatment of gastrointestinal disorders, which holds the record for US sales of an Italian-owned drug.
Click here to download an infographic on Alfasigma's two sterile departments at Alanno.
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