Compound screening against a drug target is a vital step in early stage drug discovery. Biortus has an extensive collection of testing equipment that allows development of many kinds of biochemical assays, biophysical assays, and cell-based assays. Key assays include SPR, Kinase, ADP-Glo, TR-FRET, FP, Caliper, NanoDSF, SPA etc.
Fragment screening is a relatively recent idea and has been a popular complementary method to high-throughput screening for drug discovery. Biortus has two Rule-of-3 compliant fragment libraries. All fragments are dissolved in DMSO at 100mM in 96 and 384-well format, and their aqueous solubility are at a minimum of 1mM. Depending on the expected hit rate of the target, clients have a choice of a smaller or bigger fragment library and screening of both libraries with a total of 3522 unique compounds.
For more information, please visit our website at https://en.wuxibiortus.com/Assays.html
CN
