BARDA Awards Tetraphase Antibiotic Contract
The BARDA contract includes preclinical efficacy and toxicology studies, clinical studies, manufacturing, and associated regulatory activities for TP-434.
Tetraphase Pharmaceuticals announced yesterday that the Biomedical Advanced Research and Development Authority (BARDA) has awarded it a contract worth up to $67 million for the development of TP-434, a potent new antibiotic effective against multidrug-resistant gram-negative pathogens.
The contract includes preclinical efficacy and toxicology studies, clinical studies, manufacturing, and associated regulatory activities for TP-434 as a potential treatment of inhalational disease caused by Bacillus anthracis, Francisella tularensis and Yersinia pestis.
Guy Macdonald, president and chief executive officer of Tetraphase, said,"BARDA’s award covering the development of TP-434 brings the total federal funding i
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