Baxter Healthcare Corporation

About Baxter Healthcare Corporation

Backed by over 85 years of experience in parenterals, Baxter’s BioPharma Solutions (BPS) business collaborates with pharmaceutical companies to support commercialization objectives for their molecules. BPS is a premier CMO with a focus on specialized sterile injectable manufacturing designed to meet complex and traditional sterile challenges. 

Our state-of-the-art, award-winning facilities have primary locations in: 
-Bloomington, Indiana, USA facility is a leader in sterile contract manufacturing and offers form/fill/finish services and solutions for injectables designed to meet traditional sterile manufacturing challenges.
-Halle/Westfalen, Germany facility has over 60 years of experience and is recognized as a world-class manufacturer of oncology products and other sophisticated compounds.

BPS can support your pharmaceutical needs with a broad portfolio of sterile fill/finish production capabilities, and our reputation is built on the high-quality products we manufacture for our clients in a cGMP environment. Our delivery systems include: prefilled syringes, liquid/lyophilized vials, diluents for reconstitution, powder-filled vials, and sterile crystallization. Our drug categories include: small molecules, biologics, vaccines, cytotoxics, highly potent compounds, and ADCs (antibody-drug conjugates). From formulation and development, through commercial launch, our extensive, customized support services can guide you through marketplace complexities, helping you achieve the full potential for your drug molecule. Whether you face formulation challenges, clinical supply hurdles, surges in demand due to market fluctuations, risk mitigation concerns, or patent expiry challenges, we offer tailored and versatile solutions to help achieve your commercialization objectives. 


Certifications

Baxter Healthcare Corporation

  • US
  • 2015
    On CPhI since
  • 2
    Certificates
  • 5000+
    Employees
Meet us at

CPhI Worldwide 2021

Fiera Milano, Milan, Italy
9-11 November 2021

Products from Baxter Healthcare Corporation

  • Prefilled Syringes

    Product Prefilled Syringes

    Baxter (BioPharma Solutions) offers a wide range of traditional sterile manufacturing products which includes prefilled syringes. It offers expanded small-scale through high-volume sterile manufacturing. It can increase production potential and help ensure on-time delivery to meet product demand. By providing high-speed, high-volume filling on advanced Inova Pac-Systeme, syringe-filling equipment, which mirrors filling capacity with automated inspection, labeling, and packaging equipment, it has the resources to get you to market. Patient care benefits: potential to minimize microbial contamination; potential to reduce medication dosing errors; enhanced convenience and ease of use; market benefit.
  • Antibody-Drug Conjugates

    Product Antibody-Drug Conjugates

    Baxter (BioPharma Solutions) offers a wide range of complex sterile manufacturing products which includes antibody-drug conjugates. It is a type of cytotoxics. It offers a combined approach for ADC to simplify the supply chain and provide comprehensive, coordinated and collaborative services for the development, manufacturing, and testing of bulk drug substance (BDS) and drug product (DP).
  • Biologics

    Product Biologics

    Baxter (BioPharma Solutions) offers a wide range of complex sterile manufacturing products which includes biologics. It offers innovative filling line technologies that are specifically designed to protect your biologic's integrity and optimize yield of costly API. This manufacturing process optimization helps meet the needs of biologic molecules with- 100% in-line, nondestructive weight checking; advanced cold-chain filling; dual filling technologies; high-yield process design. It provides expertise across all areas of parenteral formulation and sterile contract manufacturing such as biomolecule product formulation; process development; solution, suspension and lyophilized dosage form development.
  • Cartridges

    Product Cartridges

    Baxter (BioPharma Solutions) offers a wide range of traditional sterile manufacturing products which includes cartridges. It provides fully automated cleaning, siliconization, sterilization, filling, stoppering, and sealing; 100% automated inspection and individual cartridge loading/unloading. Conserve valuable API and improve yield with state-of-the-art sensor time/pressure system. The 100% sensor feedback reduces product waste, thus improving yield. Sizes and options: 1.5 ml, 2.7 ml, and 3.0 ml sizes; 8 mm to 14 mm diameter; 40 mm to 90 mm height; labeling options available.
  • Cytotoxics

    Product Cytotoxics

    Baxter (BioPharma Solutions) offers a wide range of complex sterile manufacturing products which includes cytotoxics. It is the most highly sophisticated and sensitive drugs to handle and produce. The barrier technology ensures your cytotoxic product is manufactured under precisely controlled temperature, relative humidity, and pressure conditions, in a clean-room grade A environment. The benefits of closed-system manufacturing includes minimized contamination risks; high-quality product development and manufacturing; employee and environmental safety. They offers the capabilities such as liquid and dry-powder filling; clinical- and commercial-scale lyophilizers; sterile crystallization; lyophilization cycle development. Integrated support services for cytotoxics includes stability storage, validation and documentation; technology transfer; analytical and microbiological services; packaging and kitting.
  • Diluents for Reconstitution

    Product Diluents for Reconstitution

    Baxter (BioPharma Solutions) offers a wide range of traditional sterile manufacturing products which includes diluents for reconstitution. It offer both customer and patient benefits. When compared to vials, they can enhance and improve patient safety such as less steps for reconstitution; reduced contamination risk; reduced risk of errors.
  • Highly Potent Compounds

    Product Highly Potent Compounds

    Baxter (BioPharma Solutions) offers a wide range of complex sterile manufacturing products which includes highly potent compounds. It presents many challenges due to the complex handling required for toxic substances. Utilizing cRABs (closed restricted access barrier system) for commercial manufacturing allows to maintain a high level of containment while a product is being manufactured. In addition, this technology maintains the integrity of the molecule, enhances product sterility and ensures the safety of the line operators. It is designed with multiple facilities under one roof with different air handling and waste disposal systems, including 100% waste collection.
  • Liquid Vials

    Product Liquid Vials

    Baxter (BioPharma Solutions) offers a wide range of traditional sterile manufacturing products which includes liquid vials. It can helps clients to meet developmental, clinical, and commercial liquid vial manufacturing needs. High-volume filling and multiple, dedicated vial-filling suites allow to expand product supply simply and cost effectively. Liquid vial filling services includes grade a environments for aseptic; formulation and filling; nonaqueous solvent development capabilities; analytical method transfer. Sizes and options: sizes from 2 ml to 100 ml; 13 mm and 20 mm sizes; inert, surface-coated, or standard stopper configurations; flip-off or tear-away seals. Filling mechanisms: linear and rotary peristaltic; time/pressure.
  • Lyophilized Vials

    Product Lyophilized Vials

    Baxter (BioPharma Solutions) offers a wide range of complex sterile manufacturing/traditional sterile manufacturing products which includes lyophilized vials. The process of freeze drying can achieve product stability, and improved shelf-life. It offers individual filling suites with lyophilization capacity, along with an intrinsically safe process that enables use of non-aqueous solvents. Sizes and options: sizes from 2 ml to 50 ml; 13 mm and 20 mm sizes; inert, surface-coated, or standard stopper configurations; flip-off or tear-away seals; intrinsically safe lyophilizers. It can help optimize cycle times and offer innovative approaches for the development of formulations and freeze-drying cycles.
  • Powder Filled Vials

    Product Powder Filled Vials

    Baxter (BioPharma Solutions) offers a wide range of complex sterile manufacturing products which includes powder filled vials. It is a type of cytotoxics. It offers filling of powder filled vials at our highly experienced Halle/Westfalen, Germany facility. In addition to continuous monitoring of temperature, relative humidity, laminar air flow, differential pressure and non-viable airborne particles in the isolator. Sizes and options: clinical to commercial scale; starting from 1 kg of powder; vial sizes from 6 to 100 ml validated; fill weight: 50 mg/vial to 5 g/vial; 1 – 8 filling heads. Advanced processing: class 100 (iso 5) isolator; isolator sterilization by vaporized hydrogen peroxide (vhp); cip/sip of powder hopper; 100% fill weight check or in-process fill weight check; auger fillers designed for precise powder dosing; online visual inspection; vial printing; packaging robot for bulk packaging of drug product vials.
  • Sterile Crystallization

    Product Sterile Crystallization

    Baxter (BioPharma Solutions) offers a wide range of complex sterile manufacturing products which includes sterile crystallization. It is a type of cytotoxics. It offers sterile crystallization of cytotoxic active pharmaceutical ingredients in a closed system. Sizes and options: poly ethylene bags (1 - 5 kg); 80 – 600 l compounding volume. Advanced processing: class 100 (iso 5) isolators for powder milling and filling; negative pressure isolator for compounding process, designed for operator safety; isolator sterilization using vaporized hydrogen peroxide (vhp); continuous monitoring of temperature, relative humidity, differential pressure and non-viable airborne particles in the isolator; aseptic transfer into powder filling isolator: final transfer of api bags using sterile rtp port; ex (explosion) proofed area.

Baxter Healthcare Corporation Resources

  • News Baxter BioPharma Solutions to manufacture Novavax COVID-19 vaccine

    Manufacturing at Baxter's Halle/Westfalen, Germany facility will help increase commercial production and promote access in UK and European markets
  • Whitepaper Seasonal Vaccine Manufacturing

    The production of seasonal vaccines, such as those for influenza, presents unique challenges to manufacturers due to the necessary time constraints resulting from annual strain selection. The limited-time span from strain selection to distribution requires most vaccine producers to rely on outsourcing partners to ensure timely production and supply. While the right facility and technical expertise are important, vaccine developers should also focus on securing a culture of speed and execution, shared expectations, and continuous improvement. This whitepaper from Baxter’s contract manufacturing business, BioPharma Solutions examines three key areas to evaluate when selecting an outsourcing partner for vaccines production to ensure quality and on-time delivery.
  • Brochure A Global Leader in Sterile Contract Manufacturing

    Our processes and systems are tailored to meet your parenteral manufacturing needs. We offer conventional sterile dosage forms, including prefilled syringes, liquid vials, lyophilized vials and cartridges as well as cost-saving diluents for reconstitution.
  • Brochure Complex Sterile Manufacturing: More Than 60 Years of Oncology Experience

    Parenteral manufacturing can be a complicated process. Cytotoxics, antibody-drug conjugates (ADCs), highly potent compounds, biologics and lyophilized products present many challenges and require specialized understanding and expertise.
  • Brochure Maximize Your Molecule's Full Potential

    We know the high-stakes challenges you face in today's complex parenteral marketplace - and how the work we do is vital to the patients you serve. That's why we work closely with you at every step to help you achieve your molecule's full potential and your commercialization objectives.