Bifiasthm®

Bifizen is a probiotic combination of 4 strains selected for complementary mechanisms of action to benefit the gut-brain axis: L. fermentum LF16, L. rhamnosus LR06, B. longum 04 and L. plantarum LP01. Bifizen supplementation for 6 weeks in healthy students showed significant benefits in depressive mood, anger, fatigue and quality of sleep. The product is now declined as a range of five for mental well-being for the whole family.

GABA Production
stimulation
Mood improvement

Stress management
Psychological functions

Bififiber is natural synbiotic based on the association of B. lactis BS01 and prebiotic fiber FOS with clinically-proven efficacy on 110 subjects with evacuation disorders. Bififiber is able to significantly alleviate symptoms of constipation, increase the number of weekly evacuations, improve stool consistency, abdominal bloating and the sense of complete emptying.

Bifisport is an innovative solution for athletes to enhance performance throughout training and competition. While intense training causes muscle inflammation and performance decrements, this association of St. thermophilus FP4 and B. breve BR03 demonstrated clinically, in athletes, to reduce inflammation and the performance loss following strenuous exercise.

Floratopic is an advanced, therapeutic probiotic product based on L. salivarius LS01 and clinically studied, in children and in adults, for the improvement of atopic dermatitis symptoms (measured by SCORAD). Importantly, LS01 is able to orientate the immune response in order to reestablish the balance from the root instead of treating only the symptoms.

Bificol is a probiotic product demonstrated clinically to improve the symptoms of Irritable Bowel Syndrome (IBS), especially abdominal bloating and pain, as well as reduce symptoms of constipation. The strains are backed by a significant scientific file demonstrating also their anti-pathogen properties, immunomodulatory and anti-inflammatory activity, their protective effect against intestinal permeability, and even their anti-oxidant function!

Bifiprost is a holistic approach to men’s urinary and prostate health. Based mainly on L. plantarum LP01 and L. paracasei LPC09, selected for their inhibition of E. coli and urinary tract pathogens as well as their metabolism of oxalates, involved in the formation of kidney stones, Bifiprost associated with saw palmetto decreased by half the prostatitis episodes, and performed significantly better than saw palmetto alone.

Acticand was developed as a probiotic medical device for vaginal application against mycosis, based on a combination of actives and probiotic strains L. acidophilus LA02 and L. fermentum LF10, selected for their inhibition capacity against Candida yeasts. Acticand was the object of two clinical studies demonstrating benefits in treatment and prevention of recurrences of vulvovaginal candidiasis and showed better results than the current standard of care. Acticand is now proposed also in supplement form for oral intake.

Activag was developed as a probiotic medical device for vaginal application against bacterial vaginosis, based on a combination of actives and probiotic strains L. plantarum LP01 and L. fermentum LF15, selected for their inhibition capacity against Gardnerella vaginalis, the main causative agent of BV. Activag was the object of a clinical study demonstrating benefits in treatment and prevention of recurrences of bacterial vaginosis and women treated were fully healed after 4 weeks at 91% (vs 20% in the placebo group) and the percentage still free from symptom was still 83% after another 4 weeks. Activag is now proposed also in supplement form for oral intake.

Aliltolactis is an oral health probiotic supplement for fresh breath, proposed in fast-melt powder to be dissolved directly on the tongue. Based on a combination of L. rhamnosus LR06, L. pentosus LPS01, L. plantarum LP01 and L. delbrueckii subsp. delbrueckii LDD01, selected for their ability to antagonize specific pathogens, it demonstrated in a human study to decrease sulphite-reducing bacteria in the saliva and two types of volatile Sulphur compounds in the mouth, which are causes of halitosis.

Bificist is proposed as a food supplement or under the status of medical device for urinary tract infections. Its composition includes a high-quality clinically-studied cranberry powder and probiotic strains L. plantarum LP01 and L. paracasei LPC09 – with compatibility and stability tested and guaranteed 24 months at 25°C as for all our other products. LP01 and LPC09 are strong inhibitors of E. coli and E. faecalis, the main infective agents of cystitis, and the product effectiveness was confirmed in a clinical trial in 33 women with acute cystitis.

An effective immune system is your best defense, and the right probiotics can help! The COVID-19 global crisis has led to a peak in demand for products able to stimulate immunity. Given the well-established importance of the microbiota in immune health, Chinese authorities have emitted in February an official recommendation for the use of probiotics in the treatment of patients with severe COVID-19 infection (1, 2).

Bifizen is a probiotic combination of 4 strains selected for complementary mechanisms of action to benefit the gut-brain axis: L. fermentum LF16, L. rhamnosus LR06, B. longum 04 and L. plantarum LP01. Bifizen supplementation for 6 weeks in healthy students showed significant benefits in depressive mood, anger, fatigue and quality of sleep. The product is now declined as a range for mental well-being for the whole family.

Probiotical was born in 1985 and has ever since driven the innovation in the probiotics industry. Daughter company of ALCE Microbiologic Laboratory, Italian leader in the production of lactic acid bacteria for the dairy industry, it is the first plant worldwide designed exclusively for the production of probiotic microorganisms for the pharmaceutical and nutraceutical industries. Probiotical has a very high quality positioning and is partner of globally leading pharmaceutical companies.

We offer a very broad portfolio of scientifically-backed probiotic bacteria as allergen-free lyophilized and microencapsulated raw materials, but also dedicate special attention to probiotic finished products with guaranteed stability and efficacy during all the shelf life. Finished products are proposed both under our own brands or for private label food supplements, in over 20 different functionalities.

With business all over the world, Probiotical is the partner of cho...

L. rhamnosus GG (ATCC53103) is the most studied probiotic strains worldwide with over 1000 publications, and especially recommended in pediatric diarrhea management and antibiotic-associated diarrhea but also studied across a number of other functionalities. We propose this strain in high quality, allergen-free, high concentration and as Active Pharmaceutical Ingredient, backed by the Drug Master File, for your pharmaceutical development.

Bifiasthm is a probiotic product proposed for children with asthma, in order to prevent asthmatic crises and support the balance of the immune system reactivitity. Bifiasthm is based on two strains with immunomodulatory activity targeted for allergic asthmatic subjects. A placebo-controlled clinical trial pending publication in 2020 and involving 500 asthmatic children showed that Bifiasthm was able to reduce significantly the episodes of asthma.

Bifivir is a synbiotic supplement for the immune system, based on 5 strains and prebiotic fiber. Bifivir has led, in several clinical trials involving in total nearly 900 adults, to a significant reduction in prevalence, severity and duration of respiratory tract infections and influenza-like illnesses, including flu.

Bifizen is a probiotic combination of 4 strains selected for complementary mechanisms of action to benefit the gut-brain axis, which showed significant benefits in depressive mood, anger, fatigue and quality of sleep. The product is now offered as a range of 5 products for mental well-being for the whole family.