Bohle Film Coater BFC -Pharmaceutical Film Coating

L. B. Bohle Gmbh offers a wide range of process machines which includes bohle tablet coater btc. It is the most economical alternative for all common coating applications. Benefits: it provides homogeneous mixing due to patented spirals, the gentle mechanical treatment of tablet cores to avoid edging and b...

L. B. Bohle Gmbh offers a wide range of process machines which includes compactor brc 25 and brc 100. Benefits: minimal material loss due to precise control of the compression force with an innovative electromechanical roller drive, constant ribbon properties assured with sensitive gap width control and ea...

L. B. Bohle Gmbh offers a wide range of process machines which includes vma - single pot granulator for pharmaceutical applications. It is a granulating and drying system specifically optimized for pharmaceutical applications. The flexible machine is state-of-the-art, and exceeds current gmp requirements w...

L. B. Bohle Gmbh offers a wide range of process machines which includes bohle fluid bed system bfs - bohle uni cone buc ®. It is the productive, practical and precise alternative to conventional wurster processing. it features a broad range of extension options for bottom tangential spray granulation as we...

Learn more about our comprehensive equipment which enables the production of tablets from powder to the coated tabet via batch and continuous processing.

Continuous wet granulation and drying have long been a hot topic in pharmaceutical research and development (R&D) and industry. However, there is no truly continuous fluid-bed dryer on the market that is suitable for a long process time and that meets the quality requirements described in the present article. This article outlines the experimental testing on a new R&D system (QbCon® 1) for truly continuous granulation and drying. Special attention is paid to the dryer and the resulting granules.
The results show that very narrow and reproducible residence time distributions are achieved in the dryer, which leads to uniform drying of the granules of different size classes. The process delivers consistent quality regarding moisture and particle size of the granules over several hours. When changing the conveying speed of the granules in the dryer while maintaining all other parameters, it was possible to describe the limits for a fixed process/formulation combination, ...