Camptothecin (plant extract)
|CAS Registry Number||7689-03-4|
|Details||Camptothecin is an alkaloid derived from the Chinese tree Camptotheca acuminata Decne. Camptothecin and its derivatives are unique in their ability to inhibit DNA Topoisomerase I by stabilizing a covalent reaction intermediate termed the cleavable complex which ultimately causes tumor cell death. In clinical it is widely believed that camptothecin analogs exhibited remarkable anti-tumour and anti-leukaemia activity. Application of camptothecin in clinic is limited due to serious side effects and poor water-solubility.
Solubility: Clear Yellow Solution at 1Mg/Ml in Dimethylsulfoxide.
Storage: stored in a cool and dry area. Kept sealed and away from direct light.
|Categories||APIsAlkaloids; Natural ExtractsPlant Extracts|
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