Camptothecin (plant extract)

Product description

Camptothecin is an alkaloid derived from the Chinese tree Camptotheca acuminata Decne. Camptotheca acuminata extract and its derivatives are unique in their ability to inhibit DNA Topoisomerase I, by stabilizing a covalent reaction intermediate termed the cleavable complex which ultimately causes tumor cell death. Origin: Camptotheca acuminataMolecular Formula:  C20H16N2O4 Molecular Weight:  348.36 Purity by HPLC: 98% min/99% min. 
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Specifications

CAS Registry Number 7689-03-4
Details Camptothecin is an alkaloid derived from the Chinese tree Camptotheca acuminata Decne. Camptothecin and its derivatives are unique in their ability to inhibit DNA Topoisomerase I by stabilizing a covalent reaction intermediate termed the cleavable complex which ultimately causes tumor cell death. In clinical it is widely believed that camptothecin analogs exhibited remarkable anti-tumour and anti-leukaemia activity. Application of camptothecin in clinic is limited due to serious side effects and poor water-solubility.

Solubility: Clear Yellow Solution at 1Mg/Ml in Dimethylsulfoxide.

Storage: stored in a cool and dry area. Kept sealed and away from direct light.
Categories APIsAlkaloids; Natural ExtractsPlant Extracts
Supplied from China
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Camptothecin (plant extract)

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