Custom Bonding and Chromatography Resins for Small and Large Molecule Purification

A wide range of DAVISIL® silica gel grades are available from one kg to multi-ton quantities to meet your application, performance, and economic requirements. DAVISIL® silicas are used to purify nutraceuticals, antibiotics, vaccine adjuvants, oil-based APIs, organic synthesis products (including intermediates and high-value APIs), and biologics. Compared to other competitor silica gel products, DAVISIL® silicas are available in various pore sizes with higher surface area, lower bulk density, and tighter particle size distribution.

Produced by a unique process based on purified organosilicate starting materials, VYDAC® spheroidal silicas are well-defined, highly pure, totally porous separation resins for preparative and process scale users. Developed and utilized in applications for protein, peptide, and oligonucleotide separations, VYDAC® resins provide excellent selectivity, reproducibility, and recovery.

Grace is a pioneer in silica and functionalization technologies, and its scientists continue to develop new and customized solutions beyond our standard range of products, often in close collaboration with customers. Grace’s particle engineering capabilities allow surface, pore, and particle properties to be tuned to meet a customer’s specific requirements. Furthermore, Grace can develop functionalized resins for specific chromatographic applications, including the separation of challenging isomers. Functionalization options include affinity, ion exchange, and reversed / normal phase chemistries. Companies in the nutraceutical and highly regulated pharmaceutical industries have come to depend on the superb quality and performance attributes of Grace silicas.