Product description

The HSA LAB equipment belongs to a family of non-destructive analyzers intended for monitoring headspace gas compositions in optically transparent and sealed containers. It employs a non-invasive laser-based technique for monitoring the headspace levels of gases such as oxygen, carbon dioxide and moisture content. HSA LAB is a benchtop system that can be used throughout the entire sterile parenteral product lifecycle, from early stages of development to laboratory applications to in-process control of headspace conditions and monitoring the quality and stability of production.


Headspace Analysis “HSA” is based on the Tunable Diode Laser Absorption Spectroscopy (TDLAS) method which accurately detects and quantifies gaseous concentration levels. A diode laser beam is transmitted through the container in the region above the product and below the cap/closure (headspace); laser beam is then received by a detector. The amount of light absorbed while crossing the headspace is measured and related to the target gas concentration.

The laser beam wavelength is tuned around the absorption frequency of the target gas to be monitored.

The HSA technology allows to perform a quick and accurate monitoring of headspace gas, by determining the nitrogen purging efficiency and by ensuring container closure integrity; it is applicable to sterile products that are packaged under modified atmospheric conditions or under a certain level of negative pressure.
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Supplied from Switzerland
HSA LAB

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