IFF Pharma Solutions

About IFF Pharma Solutions

We are now part of IFF. You’ve known us for decades as the makers of Avicel® and METHOCEL™ and many other strong brands, and today we’re building on that history while embracing a future of new possibilities. With decades of vital experience in the pharmaceutical industry, IFF Pharma Solutions team has a proven track record of working with customers around the globe to differentiate drug formulations and solve the toughest challenges. Couple that with a commitment to quality, and global manufacturing and regulatory expertise, we can apply our talent and technologies to enable your goals, delivering what is best for you, when you need it.

We offer a unique range of well-known excipients designed to deliver performance and cost advantages in various oral solid dosage forms. At IFF Pharma Solutions, our world thrives on balance. Expertise and innovation. Advancement and consistency. New growth and strong foundations. These elements are the ingredients for dependability and discovery—and they are what help us deliver the most essential pharmaceutical, dietary supplement and industrial polymer solutions in the industry.

IFF Pharma Solutions Showcase
Certifications
  • US
  • 2015
    On CPhI since
  • 3
    Certificates
  • 1000 - 4999
    Employees
Manufacturer/Innovator
Contact info

Products from IFF Pharma Solutions

  • Alginates: Protanal®, Manucol®, Protacid® and More

    Product Alginates: Protanal®, Manucol®, Protacid® and More

    Unique functionality for a broad range of pharmaceutical applications  
    Alginates are natural hydrocolloids extracted from sustainably harvested seaweed.  Chemically, alginates are formed from polysaccharides with building blocks comprised of salts of mannuronic and guluronic acid. The proportion, distribution, and length of these blocks determine the chemical and physical properties of the alginate molecules.

    Alginate drug delivery harnesses the unique properties of seaweed for premier performance in multiple pharmaceutical and nutraceutical applications; they impart viscosity in solutions and even form a three-dimensional gel in the presence of calcium ions. This unique functionality can be used in a diversity of applications such as controlled release dosage forms, enteric coatings, microencapsulation and stabilization in solutions and suspensions. Alginates also function as actives in some anti-reflux products.

    Reliability through decades of experience

    We have years of experience in harvesting seaweed to maximize yield and ensure batch-to-batch consistency. Our alginates are harvested from brown seaweed off the Norwegian coast, using sustainable techniques to allow for robust seaweed regrowth.

    Using our expertise in controlling naturally derived materials, we can deliver you consistent performance for your applications:

    • Cold / hot water solubility
    • Viscosity and gelation (wide range of viscosities and gel strengths available)
    • Gelation with Ca source (no need for heat treatment i.e. cold-gelling)
    • Rheology modification
    • Suspending agent
    • Water binding, high water retention efficiency
    • Film forming
    • Powerful at low concentrations
  • Avicel® Microcrystalline Cellulose (MCC)

    Product Avicel® Microcrystalline Cellulose (MCC)

    The renowned binder for tablets


    Avicel® microcrystalline cellulose (MCC) is a purified, partially depolymerized alphacellulose excipient made by acid hydrolysis of specialty wood pulp.
    For nearly 60 years, Avicel® has exceeded the performance of common pill binders by pushing the boundaries of science in tablet binding, leading to a premier product supported by true experts in the field. Today, Avicel® is produced in state of the art, GMP qualified facilities located in the US and Europe with rigid quality control and robust, flexible supply chains.

     Multiple functionalities in one product
    Avicel® PH MCC is most often used in tableting as a compression aid, flow aid, and filler for directly compressed tablets. Avicel® PH is an ideal wet granulation binder which rapidly produces robust granules that remain stable in high shear environments, enabling broad processing windows and maximizing batch to batch reproducibility.

    With the development of differentiated grades, Avicel® PH remains an indispensable pharmaceutical formulation tool, with versatile functionality:

    • Improved powder flow
    • Broad wet granulation processing windows
    • Optimum granule properties
    • Ideal tablet compactibility
    • Uniform tablet content
    • Increased batch size
    • Reduced moisture related API degradation
  • ETHOCEL™ Premium Ethylcellulose Resins

    Product ETHOCEL™ Premium Ethylcellulose Resins

    An excellent choice for modified release

    ETHOCEL™ premium ethylcellulose resins are water-insoluble polymers. They are soluble in a wide range of organic solvents, beginning with aliphatic alcohols such as ethanol and isopropanol, and are compatible with most other familiar organic solvent chemistries, including ether alcohols, ketones, aromatic hydrocarbons and many more.

    Beyond barrier membrane coatings

    As a water insoluble film-forming material, ETHOCEL™ polymers are useful for taste masking pharmaceutical active ingredients in addition to forming controlled release coatings for multiparticulates or providing an additional moisture barrier for water sensitive ingredients.  

    ETHOCEL™ polymers also have excellent thermoplastic properties and are capable of being melt extruded into various forms. Fine powder (FP) grades of ETHOCEL™ can be compressed to form hydrophilic matrix tablets for oral controlled release with a non-gel forming mechanism which provides an alternative drug release profile as compared to traditional alternatives.

  • GRINDSTED® Xanthan Gum

    Product GRINDSTED® Xanthan Gum

    GRINDSTED® Xanthan Gum is a naturally fermented product of carbohydrates and is applied in various liquid, semi-solid and solid pharmaceutical dosage forms. 

    Application in pharmaceutical formulations

    GRINDSTED® Xanthan Gum readily dissolves in water under ambient conditions without the need of special high-shear equipment. As one of the most robust and efficient excipients, it tolerates high salt content, high temperature and is stable in a wide pH range. Low use levels of GRINDSTED® Xanthan Gum are sufficient to provide desired viscosities and textures. At the same time, its pronounced shear-thinning behavior enables handling of even highly viscous solutions. 

    Key Benefits:
    • Suspending agent for solids and oil droplets
    • Effective emulsion and foam stabilization
    • Low use level required (0.05-1%)
    • High viscosity at low concentration with pronounced shear-thinning behavior
    • Anti-syneresis effect
    • Stable in both acidic and alkaline solutions (approximate pH window 2-12)
    • Resistant to high temperatures
    • Compatible with solutions containing high concentrations of various salts
  • METHOCEL™ Cellulose Ethers

    Product METHOCEL™ Cellulose Ethers

    Well-recognized product that can do it all


    METHOCEL™ cellulose ethers are water-soluble polymers derived from cellulose. The METHOCEL™ product range encompasses methylcellulose and hydroxypropyl methylcellulose (hypromellose) – each available in different grades to address a wide range of applications including tablet coatings, granulation, controlled release, drug layering, vegetarian hard-shell capsules and amorphous drug stabilization. 

     
    Reliable and multi-functional
    METHOCEL™ products have been in continuous production for more than 70 years with production facilities and deep product expertise located around the globe.

    The METHOCEL™ Premium family of water-soluble polymers for pharmaceutical applications offers exceptional flexibility and a broad range of properties typically not found in other water-soluble polymers. In many applications, two, three or even more ingredients may be needed to do the same job performed by one METHOCEL™ product. That means one ingredient can do the job of many, saving money and time.

  • TEXTURECEL™

    Product TEXTURECEL™

    Ingenious ingredient for many pharmaceutical applications

    TEXTURECEL™ is highly purified sodium carboxymethyl cellulose (NaCMC) that forms clear solutions in water at all temperatures, has exceptional water binding properties, and is available in a wide range of viscosity grades. 

    Efficacy in many dosage forms

    TEXTURECEL™ NaCMC is applied in oral solids, such as granules and pellets, powders as well as coatings for tablets. It is highly versatile and is therefore also widely used in topicals and semi-solid & liquid dosage forms, including ointments, creams, gels, pastes, solutions, suspensions, and emulsions. Our customers around the world enjoy the benefits of TEXTURECEL™ NaCMC in various wound care products, too.

    Key Benefits:
    • Adjusts the rheology of solutions
    • Functions as thickener, stabilizer, binder or protective agent
    • Soluble in hot and cold water
    • Clear and transparent solutions
    • High water binding capacity
    • No taste or odor
    • Physiologically inert
    • Compatible with other excipients

IFF Pharma Solutions Resources

  • Sponsored Content IFF Pharma Solutions: Paving the Way for Superior Suspensions

    Shawn Branning, Global Strategic Marketing Manager at IFF – Pharma Solutions
  • Brochure IFF Pharma Solutions Product Portfolio

    With decades of vital experience in the pharma industry, we have a proven track record of working with customers around the globe to differentiate drug formulations and solve the toughest challenges with our robust excipients portfolio. Find out more.
  • News Biologics manufacturing and diagnostics need resiliency, says Scott Gottlieb

    Former FDA Commissioner lays out roadmap for building out excess capacity to deal with pandemic situations
  • Brochure Enabling Technologies in Suspensions

    Our experts can help you design an optimal liquid or semi-solid application using our broad portfolio of specialized excipients and deep expertise in suspensions. Find out more.
  • Brochure Meet IFF Pharma Solutions

    Meet the makers of Avicel®️ and METHOCEL™️. Delivering expertise, innovation, and a passion to solve for drug delivery. Find out more
  • Brochure AVICEL®️ MCC & Related Co-processed Products

    For nearly 60 years, Avicel®️ has exceeded the performance of common pill binders by pushing the boundaries of science in tablet binding, leading to a premier product supported by true experts in the field. Find out more.
  • Brochure Smart Pharma Solutions with Reliable Products

    We have the excipients and APIs that can help you meet your formulation needs. When you need a pharmaceutical solution and the technical expertise to put it to work quickly in your formulation, there are more reasons than ever to rely on us. Our products comply with the requirements of Food and Drug Administration (FDA), Food Chemicals Codex, Codex Alimentarius, United States Pharmacopeia (USP), National Formulary (NF), Japanese Pharmacopoeia, European Pharmacopoeia and British Pharmacopoeia. In addition, they can meet most requirements of Chinese Pharmacopoeia.
  • Brochure Dietary Supplements Solution Portfolio

    At DuPont Nutrition & Biosciences (N&B) we understand dietary supplements. Backed by decades of expertise and a vast portfolio of solutions, we collaborate with you to turn your ideas into shelf-ready products in a variety of dosage forms. Whether you’re searching for clean label, plant-based and consumer-friendly capsules, great tasting gummies or creating smaller tablets for consumer convenience, we’re here to help every step of the way.
  • Brochure Smart Pharma Solutions: Essential Excipients and Vital Expertise to Help Customers Thrive

    Because Health Matters
    At DuPont, we aim to help our pharma customers overcome everyday challenges and innovate future solutions. Armed with essential excipients and vital expertise, our broad portfolio is designed to deliver performance and cost advantages in various oral solid dosage forms. Couple that with leading QbD programs, regulatory expertise and a wide network of global problem solving experts, we can help deliver a consistent, high-quality offering, at the right time, every time.
  • Brochure Avicel® Selection Guide

    A versatile excipient addressing your critical formulation needs
    Functionalities tailored to requirements of dosage form, formulation and technology. With the development of differentiated grades, Avicel® remains an indispensable formulation tool, boosting productivity and meeting tough formulation challenges. 


    Contact DuPont for assistance with choosing the optimal Avicel® grade or for help with your tableting formulation issues.
  • Whitepaper Make Direct Compression of CR Tablets: Efficient & Cost-Effective

    Direct compression could simplify production of hydrophilic matrix tablets, but this method historically has often been challenging due to poor flow properties and low compressibility of powder blends —until now. This whitepaper will reveal how DuPont Nutrition & Biosciences’ unique portfolio and deep expertise can provide several options to make effective production of hydrophilic matrix tablets more convenient and cost-effective than ever.
  • Whitepaper Sodium Alginate for Anti-reflux Suspensions – Study of Effect of Alginate Quality and Formulation Variables

    Treatment for GERD (gastroesophageal reflux disease) is generally targeted for gastric acid neutralization and suppression of gastric acid production and/or secretion. However, another key approach to alleviate the condition is minimizing the exposure of the esophagus to acidic refluxate via raft-forming anti-reflux preparation wherein a viscous gel forms a physical barrier above the stomach contents and prevents it from refluxing back into the esophagus. This whitepaper from DuPont provides key insights into how sodium alginate acts as the key functional ingredient in anti-reflux formulations but also how the combined functionality of all ingredients creates the raft forming function via optimum concentration in formulation.
  • Video Paediatric Drug Delivery: Challenges and Solutions

    This session was originally broadcast as part of the CPhI Worldwide 2021 digital content programme. Developing medicines for the pediatric population can be challenging, requiring different formulations, dosage forms and strengths, or different routes of administration. This session explores the hurdles and emerging opportunities to develop an optimal drug delivery addressing issues such as adherence and acceptability in the pediatric population. Critical development & administration challenges for paediatric medicines New technologies for developing and delivering optimal dosage forms Advantages and Disadvantages of Standards and Novel Strategies for Drug Administration in Paediatrics Emerging Opportunities
  • Video Podcast: Ensuring Reliable Quality in Excipient Products

    In this podcast episode, Kieran O'Dwyer, Global Quality Leader at DuPont Nutrition & Health, meets with our editor Gareth Carpenter to discuss excipients products and ensuring a consistent level of quality. Kieran is a speaker at the CPhI Festival of Pharma. This podcast was originally aired as part of the CPhI Festival of Pharma.
  • Video The Landscape of Affordable Healthcare

    The changing landscape for coverage of healthcare services and medical products is creating new challenges in making sure patients have affordable access to care, and that those financing these opportunities can sustain these investments. How we can develop sustainable models for covering the cost of new innovations and modernize our payment models; to make sure that patients have access to the medical care they need without bankrupting our healthcare system. What are the new models for healthcare delivery that we’ll need to embrace? CPhI is delighted to welcome, Dr. Scott Gottlieb, who served as the 23rd Commissioner of Food and Drugs, for our regulatory keynote. Aired as part of the CPhI Festival of pharma
  • Video The Landscape of Affordable Healthcare

    The changing landscape for coverage of healthcare services and medical products is creating new challenges in making sure patients have affordable access to care, and that those financing these opportunities can sustain these investments. How we can develop sustainable models for covering the cost of new innovations and modernize our payment models; to make sure that patients have access to the medical care they need without bankrupting our healthcare system. What are the new models for healthcare delivery that we’ll need to embrace? CPhI is delighted to welcome, Dr. Scott Gottlieb, who served as the 23rd Commissioner of Food and Drugs, for our regulatory keynote. Aired as part of the CPhI Festival of pharma
  • Video DuPont Pharma Solutions Value Proposition

    DuPont Pharma Solutions draws from the rich experience and expertise of historically market-leading excipient companies who pioneered brands like Avicel®️, the first pharma tablet binder, METHOCEL™️, a leading brand across multiple applications, Ac-Di-Sol®️, a superdisintegrant, and POLYOX®️, a thermoplastic solution with varied functionality. Our pharma-dedicated global research facilities and a wide manufacturing network locate us close to our customers. This short video summarizes the value proposition we offer to our customers.
  • Video METHOCEL™ Cellulose Ethers

    Do you know that METHOCEL™ is one product that can do it all – and has been in continuous production for over seven decades? Pharmaceutical companies are continuously looking for ways to innovate – through new technologies such as controlled release systems and oral films, or through faster and more efficient manufacturing processes. METHOCEL™ Premium family of products offers exceptional flexibility and a broad range of properties typically not found in other water-soluble polymers.
  • Video ETHOCEL™ Premium Ethylcellulose Resins

    Do you know that ETHOCEL™ Premium Polymers are an excellent choice for modified release applications in pharmaceuticals? Available in many viscosity grades with high purity, this range of water-insoluble polymers is essentially tasteless, colorless, odorless, and very inert physiologically. As a water insoluble film-forming material, ETHOCEL™ polymers are useful for taste masking pharmaceutical active ingredients in addition to forming controlled release coatings for multiparticulates or providing an additional moisture barrier for water sensitive ingredients.