Inhaled Formulation Development

Inhaled Formulation Development
Product Description

With expertise in powder and liquid formulations for small molecules and biologics, as well as a broad portfolio of proprietary device and formulation technologies, we can help you overcome the challenges of inhaled formulation development.

Dry Powder Formulation
Advanced powder blends
Spray-dried, particle engineered formulations
Formulations for non-proprietary capsule devices

Liquid Formulation for Nebulisation
Aqueous solutions and suspensions optimised for smart nebuliser delivery
Freeze-dried powders for reconstitution

Non-Aqueous Liquid Formulation for pMDI
Non-aqueous pressurised solutions and suspensions using HFA propellants
Matched API, formulation and in vitro performance for generic programmes

VECTURA GROUP PLC

  • GB
  • 2020
    On CPhI since

VECTURA GROUP PLC

  • GB
  • 2020
    On CPhI since

More Products from VECTURA GROUP PLC

  • Inhalation Device Platforms

    Product Inhalation Device Platforms

    Access the delivery technology best suited to the needs of your development programme, including unit-dose and multi-unit dose DPIs, pMDIs and smart nebulisers, suitable for home or hospital applications.

    Dry Powder Inhalers:
    Options include proprietary unit- and multi-unit dose platforms, as well as off-the-shelf capsule devices, to support your programme from early development through to a commercial-ready device.

    Nebulisers:
    Our state-of-the-art breath-actuated nebulisers with guided inhalation have been developed to improve lung delivery for inhaled drugs, with the aim of achieving better clinical outcomes and/or shortened treatment times.

    Metered Dose Inhalers:

    With extensive expertise in pMDI development and lifecycle management, we can help develop a new pMDI product or optimise your existing formulation and device performance. 

  • Analytical Services - Inhaled Products

    Product Analytical Services - Inhaled Products

    With extensive, state-of-the-art analytical testing facilities and equipment, our expert teams are able to develop and validate the methodologies required to characterise inhaled delivery platforms, especially DPI, pMDI and nebulised products.

    To ensure seamless support for your development, we also offer:
    Comprehensive stability storage facilities able to support small bespoke stability studies through to large pivotal programmes.
    Deep experience of development pharmaceutics, device verification testing and authoring of CMC sections for regulatory submissions.
  • Process Development & Inhaled Product Manufacturing

    Product Process Development & Inhaled Product Manufacturing

    In addition to extensive development manufacturing facilities, Vectura has GMP manufacturing facilities for dry powder inhalers, pMDI and nebuliser medical devices as well as further capability to handle biological molecules. 

    Our GMP manufacturing facilities and equipment are relevant-to-commercial scale, meet all required EHS, Quality and Regulatory standards and are operated by a dedicated manufacturing team.

  • Medical & Regulatory Services - Inhaled Products

    Product Medical & Regulatory Services - Inhaled Products

    Our formulation, device and development services are supported by our medical, regulatory, device vigilance and pharmacovigilance teams to safeguard your programme and ensure the smoothest path to product approval.

    Our in-house team can support with:

    Global regulatory development strategy and submission expertise (NCEs and generics)
    Medical devices and combination products including compliance with the EU Medical Device Regulation (MDR)
    Global pharmacovigilance and device vigilance capabilities
    Clinical strategy and protocol development
  • Dry Powder Inhalers (DPI)

    Product Dry Powder Inhalers (DPI)

    Our dry powder inhalers are derived from the commercially-validated AirFluSal® Gyrohaler® platform, but with a range of user interfaces and payload volumes, giving you confidence of performance and a proven regulatory track record.

    With options for proprietary unit- and multi-unit dose platforms, as well as off-the-shelf capsule devices, we can support your programme from early development through to a commercial-ready device.

  • SMART Nebulisers

    Product SMART Nebulisers

    Our state-of-the-art breath-actuated nebulisers with guided inhalation have been developed to improve lung delivery for inhaled drugs, with the aim of achieving better clinical outcomes and/or shortened treatment times.

    FOX® nebuliser: handheld system that delivers high performance using a vibrating mesh technology. FOX® is suitable for the delivery of small molecules and biologics, formulated as solutions or nano-suspensions. The device has a 510(k) premarket notification for marketing in the US. 

    AKITA® JET nebuliser: desktop system which uses proprietary positive pressure technology to assist drug delivery to the lungs. Potential as multi-patient device in hospital setting. The device is CE-marked and has a 510(k) premarket notification for marketing in the US.
  • Tailored Inhaled Development Services

    Product Tailored Inhaled Development Services

    From one-off studies and specialist techniques through to full development services, our inhalation services can support your programme through all stages of clinical development and get your product ready for commercial manufacturing.

    We understand different customers may require different types of collaborations. You may be working in a biotech company with an early-phase molecule, looking for fast progression to the clinic and proof-of-concept, or you may be part of a large pharmaceutical company trying to overcome a technical challenge, or looking for a solution to de-risk your programme.

    With over 20 years’ experience in inhaled product development, and a track record of helping customers, partners and licensees succeed in bringing inhaled medicines to market, you can trust us with your product candidate.



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