Webinar
15 Nov 2022

Innovation – Addressing Patient Compliance and Enhancing Consumer Experience

It’s a hard pill to swallow, but medication adherence is a crucial issue today. For oral formulations in pharma and nutraceuticals, taste, appearance, and aroma directly impact patient compliance and consumer experience.

Choosing the right excipients to provide optimum performance while continuing to appeal to patients and consumers alike is critical in bringing finished formulations to market.

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ROQUETTE FRERES SA

  • FR
  • 2015
    On CPHI since
  • 5000+
    Employees
Company types
Manufacturer/Innovator

Other Content from ROQUETTE FRERES SA (5)

  • News Roquette to advance drug delivery research with new US Innovation Center

    The new facility will focus on the research of excipients for oral dosage forms, drug delivery systems, nutraceutical APIs and innovative pharma ingredients
  • Brochure BROCHURE - Roquette Pharmaceuticals and Nutraceuticals

    Discover the wide range of products by Roquette in Pharmaceuticals and Neutraceuticals
  • News Vaccine manufacturing demand has had limited effect on regenerative medicine sector, panel tells CPHI audience

    The ramping up of vaccine manufacturing demand amid the COVID-19 pandemic had an initial impact on cell and gene therapy production but the regenerative medicine sector has largely weathered the storm, according to senior industry figures in a recent panel discussion at the CPHI Festival of Pharma virtual event.
  • Video Polysorbates versus Hydroxypropyl Beta-Cyclodextrin (HPBCD) Stability Comparative Study and their Monoclonal Antibody Stability Benefits

    Polysorbates are intensively used in biologics formulation as stabilizer due to their propensity to inhibit aggregation at interfaces but possess low intrinsic stability. In this study, the chemical stability of KLEPTOSE® HPBCDs are compared with polysorbates under various stress conditions.

    When subjected to heat stress and other chemical stressors – autoclave, light and oxidative stresses – HPBCD remains almost stable while polysorbates show more severe degradation. Further, profiling characterization and degradation analysis reveal that HPBCD chemical structure remains intact while polysorbates undergo significant hydrolytic degradation and oxidation.

    Lastly, the physicochemical stability of monoclonal antibody in formulations have been investigated using adalimumab as a model protein. When subjected to light stress, HPBCD-containing formulations show significant decreases in protein aggregation, as well as superior monomer and total protein recovery compared to polysorbate-containing formulations. HPBCD also reduces both agitation and thermal stress-induced protein aggregation and prevents sub-visible particle formation compared to polysorbates.


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  • Webinar Latest Trends in Consumer Health

    Worldwide, people are increasingly health-conscious and aware of the impact of individual lifestyle choices on their health and the health of others. In the latest years, consumers seek more and more transparency from companies through their brand, product manufacturing, and actions that promote well-being for the world around them. While also looking for more affordable, accessible, and personalized product experiences. This session explores the latest news and insight on consumer health, including how pharma engages patients in education and decision-making.