Japan's Kissei to Support COPD Therapy Development
Kissei Pharmaceutical is to fund $2.5m to support further clinical development of MediciNova's MN-221 to treat acute exacerbations of asthma or chronic obstructive pulmonary disease.
Japan's Kissei Pharmaceutical will pay California-based biopharmaceutical company MediciNova $2.5m to support further clinical development of MN-221, a novel, highly selective, beta(2)-adrenergic receptor agonist, for the treatment of acute exacerbations of asthma or chronic obstructive pulmonary disease (COPD).
MediciNova is currently conducting a Phase 2b study in patients with acute exacerbations of asthma in the US. In the Phase 1b clinical study, MN-221 demonstrated improvements in forced expiratory volume in one second (FEV1) with no clinically relevant safety concerns in patients with stable, moderate to severe COPD.
In all the asthma trials, MN-221 demonstrated improvements in FEV1 as well as a 45% decrease in hospitalisation r
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