Klucel™️ hydroxypropylcellulose (HPC)

Ashland offers a range of excipients and technologies, polymer expertise, and technical support for oral solids, liquids, and parenteral dosage forms. Our solutions include controlled release, binders, disintegrants, solubles, stabilizers, rheology modifiers, and resorbable polymers.

Viatel™️ bioresorbable polymers are designed to support the needs of injectable drug formulation and medical device strategies in a broad range of applications including controlled release, degradable medical devices, and emerging applications in the wider field of advanced drug delivery.

Benecel™️ XRF HPMC products are optimized for controlled-release matrix tablets providing robustness and consistent drug release, especially for high-speed tableting operations. Hypromellose is the most successful polymer for hydrophilic matrix tablets, the dominant technology for controlled-release applications.

Ashland’s Klucel™️ hydroxypropylcellulose (HPC) is a nonionic water-soluble cellulose ether with a remarkable combination of organic solvent solubility, thermoplasticity, and surface activity with aqueous thickening and stabilizing properties.

An overview of product grades available for Ashland's pharmaceutical excipients.

Product sell sheet for Benecel™ XR and XRF HPMC.

Product brochure for Klucel™ EXF Ultra HPC.

An overview of Aquarius™ film coating systems available for pharmaceutical applications.

An overview of Aquarius™ film coating systems available for nutraceutical applications.

This session was originally broadcast as part of the CPHI Worldwide 2021 digital content programme. The session discusses: Challenges faced when removing TiO2 from film coatings Aquarius TM TF. A reliable and effective alternative to TiO2 in film coatings Improved process economics with Aquarius Genesis TF high-solids TiO2-free film coating

Hydrophilic polymer matrix systems are widely used in oral controlled drug delivery because of their flexibility to obtain a desirable drug release profile, cost effectiveness, and broad regulatory acceptance.

Hydroxypropyl methyl cellulose (HPMC) is the key matrix former used in the majority of formulations. As controlled release formulations continue to evolve, so does the need for more robust and flexible matrix forming polymers. Join this learning lab session to:
understand key mechanistic aspects of hypromellose-enabled hydrophilic matrix tablets discover how polymer engineering results in optimized Benecel HPMC grades (new Benecel XR & XRF HPMC grades) learn about the advantages of Benecel DC Hypromellose in flow and loss-in-weight (LIW) feeding for continuous manufacturing compared to regular HPMC grades



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