Major changes for bio supply forecast in 2018 by bioLIVE

19 Dec 2017

Integration of supply chain a critical issue as industry globalises, with a resurgence in European manufacturing and biotech markets forecast.

Industry experts from bioLIVE – the new UBM biomanufacturing and bioprocessing event taking place next year in Madrid (9-11 October) – predict that 2018 will usher in a new age of increased integration and collaboration across the large and small molecule supply chain. Next year will also see a continued rise in the European bioprocessing and biomanufacturing sectors, along with a resurgence in European biotechs.

Major changes for bio supply forecast in 2018 by bioLIVE

Experts at UBM have been studying market developments ahead of the new event’s launch, and one of the key factors identified is the relative states of maturity of the supply chains. The small molecule space has nearly 50 years of history behind it, coupled with a highly mature contract services sector, whereas for newer biologicals, such as cell and gene therapies, the potential development and commercialisation challenges that lie ahead are only starting to emerge.

“One of the consistent problems in bio for the last year has been getting the right level of skilled workers, as well as building a global and stable partners base. This is an area that small and large molecule will likely collide in 2018 – particularly as more CDMOs, and pharma companies begin to diversify their capabilities,” commented Rutger Oudejans, Brand Director Pharma at UBM.

Overall, the biologics market in Europe is experiencing fairly robust growth and there is a resurgence of activity in the European bio hubs, but the supply chain will be a key area of focus to ensure that products make it to market quickly and securely.

Another consideration is that, at present, the US and Europe dominate manufacturing, but China and India are widely acknowledged to be fast growing bio markets albeit from a small base. As seen with small molecules 30 years ago, biosimilars development will gradually move East. However, this will happen on an even faster timeline due to the greater sizes of the domestic markets here now – which are far more developed than when the generics industry was evolving.

UBM research amongst the potential supplier base is showing that 2018 will be a critical year for the bio industry. There is a clear duality in the market as the industry tries to incorporate increasing demand for biosimilars (often large mammalian capacity demand), coupled with the unique development challenges of the newer smaller cohort drugs – single-use tech is another major growth area. Collectively, this means there are potentially two distinct types of supply chain developing – and in multiple geographic locations. And that is without considering the differences in upstream and downstream processing.

Next year, there is likely to be an increased internationalisation of the market as Asian companies will move to work with more western partners, and in- and out-licensing of newer more efficient technologies will proliferate to help lower overall costs.

“In the past few years, we have seen the supply chains of bio and small molecule coming together, particularly as you have seen more and more CDMOs transferring their skills into bio. There is a growing issue of availability of resource, and undoubtedly there are learnings and contacts that can be shared, since there is a global shortage of skills and manufacturing. For bioLIVE, this is a significant opportunity. We will need to pull in our global partners from China and India to next year’s event, but also centralise the European and US bio markets, which are still somewhat disparate. By mirroring what has already been achieved for small molecules we will create a hub greater than the sum of its parts, as we connect across geographies and bring together companies from both the processing and manufacturing supply chain. It’s a very exciting time for the industry, as next year we foresee a more mature supply chain beginning to take hold,” added Oudejans.

In Europe, CMOs are predicted to align their strategies to not only address capacity, but also the greater complexity of products, supplier risk and the adoption of advanced biomanufacturing technologies.

Finally, 2018 – as highlighted by the CPhI Annual Report – could also be the year we see the development of new, bio specific excipients. These new excipients are likely to be developed in conjunction with a bio active and there will be a focus on characterising excipients by surface interaction. However, biosimilars are not predicted to drive down costs of these new excipients for biologics, since biologics will still have superior pharmaceutical equivalence.

Read More

Related news

Innovation awarded at Pharmapack

Innovation awarded at Pharmapack

10 Feb 2020

Innovations across primary and secondary packaging, drug delivery devices, and machinery acknowledged in Exhibitor Innovations, with Health Product Awards for patient-centricity and eco-design.

Read more 
Digital value-added medicines - a key driver for 2020

Digital value-added medicines - a key driver for 2020

29 Jan 2020

Pharmapack also identifies waste management and the use of blockchain as key trends for the year ahead.

Read more 
CPhI and AAPS partner to expand expert scientific content at CPhI North America

CPhI and AAPS partner to expand expert scientific content at CPhI North America

10 Jan 2020

CPhI and the American Association of Pharmaceutical Scientists (AAPS) today announced a partnership to expand the scientific content of activities sponsored by CPhI, including CPhI North America—the only event to bring the entire North American pharmac...

Read more 
Innovation and regulatory harmonisation to drive Indian pharma in 2020

Innovation and regulatory harmonisation to drive Indian pharma in 2020

18 Dec 2019

Experts suggest the continued goal of aligning India to Western regulatory standards will help the country sustain significant increases in exports.

Read more 
Connectivity, customization and sustainability driving packaging and drug delivery in 2020

Connectivity, customization and sustainability driving packaging and drug delivery in 2020

4 Dec 2019

Pharmapack 2020 gathering top specialists and pioneers to exchange their vision on best strategies to tackle key challenges.

Read more 
Worldwide event predicts global pharma trends for 2020

Worldwide event predicts global pharma trends for 2020

27 Nov 2019

Content sessions identify value-added medicines, preventive drugs, early diagnostics and patient experience as some of the trends for the year ahead.

Read more 
India pharma forecast to grow strongly in 2020

India pharma forecast to grow strongly in 2020

22 Nov 2019

The rise in exports growth potential is believed to be in response to concerted reforms by the CDSCO and industry quality improvements in the last few years.

Read more 
Winners of the 16th Pharma Awards

Winners of the 16th Pharma Awards

11 Nov 2019

Companies and individuals from across the whole pharma supply chain recognised for their excellence and commitment.

Read more 
CDMOs to benefit from rising BTDs, orphan drugs and fast track status therapies

CDMOs to benefit from rising BTDs, orphan drugs and fast track status therapies

8 Nov 2019

But personalized medicines will require new logistics and manufacturing systems.

Read more 
Europe predicted to surpass the US in biologic manufacturing capacity by 2023

Europe predicted to surpass the US in biologic manufacturing capacity by 2023

6 Nov 2019

Demand for biological manufacturing is growing faster than capacity growth.

Read more