Malvern Instruments Launches its New OMNISEC GPC/SEC
A completely new gel permeation/size exclusion chromatography (GPC/SEC) platform from Malvern Instruments breaks new ground in delivering the high performance, ease of use and productivity demanded in today’s analytical laboratories. Malvern’s innovative OMNISEC platform integrates highly efficient sample separation via the OMNISEC RESOLVE module and high sensitivity analysis using OMNISEC REVEAL, a fully integrated multi-detector array. The system has applications wherever there is a need for detailed analysis and understanding of natural or synthetic polymers, proteins and macromolecules.
GPC/SEC is a two-step analytical process that involves separating a sample on the basis of its size and then analyzing the resulting fractions. The technique delivers molecular weight, molecular size and structural information, all of which define the performance of many industrially important materials. Coupling the efficient sample separation of OMNISEC RESOLVE with the fully optimized, multi-detector, information-rich analysis delivered by OMNISEC REVEAL, Malvern has produced a market-leading solution for researchers and formulators developing novel natural and synthetic polymers, pharmaceutical and biopharmaceutical products and foods.
OMNISEC REVEAL includes the following four detectors: refractive index (RI), UV/Vis Photodiode array (UV-PDA), low angle/right angle light scattering (RALS/LALS) and viscometer. Its light scattering detector is the most sensitive on the market meaning it can accurately measure molecular weights as low as 200 Da or injection masses of 100 ng. A new self-balancing viscometer design with a user exchangeable capillary bridge boosts instrument productivity and cuts lifetime costs by extending viscometer life, reducing instrument downtime and minimizing maintenance requirements. Excellent temperature control across the complete module, including the integrated detectors and inter-detector tubing, further boosts the accuracy of all measurements.
OMNISEC RESOLVE consists of a sample degasser, pump, autosampler and column oven, each optimized for precise, high resolution separations. This translates into smooth stable baselines for detector analysis, which in turn boost the accuracy of all measurements. Key features here include a low volume, high efficiency degasser design that enables rapid switchover from one sample type to another, thereby delivering substantial timesaving in busy multi-user labs. The new temperature controlled autosampler eliminates injection waste, minimizing the sample required for routine measurement, and in combination with the column oven maintains all samples under closely controlled conditions throughout the analysis. This is especially important when dealing with materials such as proteins which can be temperature sensitive.
As well as the complete OMNISEC system, OMNISEC REVEAL can be purchased as an individual detector module to add to an existing GPC/SEC system. However, there are substantial advantages to an integrated system, with benefits including: smaller inter-detector volumes, reduced band broadening and better temperature control. These deliver improved sample stability and enhanced accuracy, and the day-to-day productivity efficiencies that stem from using a system that has been fully and optimally integrated to meet modern GPC/SEC requirements.
Related News
-
News Patients vs Pharma – who will the Inflation Reduction Act affect the most?
The Inflation Reduction Act brought in by the Biden administration in 2022 aims to give better and more equitable access to healthcare in the USA. However, pharma companies are now concerned about the other potential costs of such legislation. -
News CPHI Podcast Series: What does the changing US Pharma market mean for industry and patients alike?
In this week's episode of the CPHI Podcast Series Lucy Chard, Digital Editor for CPHI Online is joined by James Manser to discuss the political and market changes in the US pharma field. -
News CPHI Barcelona Annual Report illuminates industry trends for 2024
The CPHI Annual Survey comes into it’s 7th year to report on the predicted trends for 2024. Over 250 pharma executives were asked 35 questions, with their answers informing the industry landscape for the next year, spanning all major pharma marke... -
News Which 10 drugs are open to price negotiation with Medicare in the USA?
The Centres for Medicare & Medicaid Services, under the Biden administration in the USA, has released a list of the 10 drugs that will be open to price negotiations as part of the new legislation under the Inflation Reduction Act (IRA). -
News EU Medical Devices Regulation causes unintended disappearances of medical devices for children, doctors state
Doctor groups and associations have appealed to the EU to correct the EU Medical Devices Regulation law that may cause unintended shortages of essential drug and medical devices for children and rare disease patients. -
News 10 Major Drug Approvals So Far in 2023
Last year, 37 novel drugs were approved by the FDA, this was a high number for such a category, and covered many fields including oncology, demonstrating how promising further research is, and how it is only continuing to build. To date, there are alre... -
News Detecting Alzheimer's disease with a simple lateral flow test
A novel rapid diagnostic test for early-stage Alzheimer's disease has been developed using a biomarker binder from Aptamer Group along with technology from Neuro-Bio, the neurodegenerative disease experts. -
News CPHI Podcast Series: outsourcing and manufacturing trends
Listen to the CPHI Podcast Series this June to hear Gil Roth of the PBOA speak with Digital Editor Lucy Chard about the biggest trends and topics to watch in pharma outsourcing and manufacturing at the minute.
Position your company at the heart of the global Pharma industry with a CPHI Online membership
-
Your products and solutions visible to thousands of visitors within the largest Pharma marketplace
-
Generate high-quality, engaged leads for your business, all year round
-
Promote your business as the industry’s thought-leader by hosting your reports, brochures and videos within your profile
-
Your company’s profile boosted at all participating CPHI events
-
An easy-to-use platform with a detailed dashboard showing your leads and performance