Mogrify wins Business Weekly award for ‘Disruptive Technology’

25 Mar 2019

Direct cellular conversion technology recognized at prestigious business awards.

Cell Mogrify, a UK company aiming to transform the future development of cell therapies, has won the ‘Disruptive Technology’ category at the Business Weekly Awards, in recognition of its novel bioinformatic platform, which is built upon a decade of world-class multidisciplinary science.

Mogrify wins Business Weekly award for ‘Disruptive Technology’

Mogrify’s proprietary direct cellular conversion technology takes a systematic big-data approach (Rackham et al., Nature Genetics, 2016) to identify the factors needed to drive the conversion of one mature human cell type into any other without going through a pluripotent stem cell- or progenitor cell-state.

Mogrify’s approach is faster and more accessible than iPSC-based protocols as it doesn’t require a licence to use Yamanaka factors to induce pluripotency, it eliminates the need for a two-step approach involving reprograming and differentiation to allow for one-step transdifferentiation, and it produces mature cells rather than converting stems cells to progenitor cells via methods that mimic natural development, which can be slow and time-consuming.

The Company is applying its patented technology to generate IP and accelerate the development and manufacture of regenerative cell therapies across every therapeutic area.

Professor Julian Gough, Co-founder and CSO, Mogrify, said: “This award is testament to the dedication of Mogrify’s multidisciplinary team who have invested their time and expertise in bioinformatics, cell reprograming and machine learning to deliver a direct cellular conversion platform, powered by next-generation sequencing and gene-regulatory data. Mogrify’s mission is to transform the future of cell therapy and it is an honor to have our disruptive technology recognized at the Business Weekly Awards.”

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