New Single-Use Fermentor Brings Microbial Applications Up to Speed
A new single-use fermentor matches the performance of stainless steel while eliminating clean/steam-in-place steps, reducing set-up time and mitigating cross-contamination risk in microbial fermentation.
The Thermo Scientific HyPerforma Single-Use Fermentor (SUF) is the first single-use system specifically engineered for microbial fermentation and designed to scale up from the lab to GMP production. Capable of meeting the aggressive performance demands of industrial microbiology, the HyPerforma SUF integrates into existing Thermo Scientific single-use technologies to achieve exceptional efficiency and scalability across the entire bioprocessing workflow.
Thermo Fisher will showcase its new HyPerforma Single-Use Fermentor this week at the BioProcess International Conference and Exhibition, 21–23 October 2014 at the Hynes Convention Center, Booth #301.
“Until now, fermentation equipment has been hard to convert to single-use due to the aggressive demands of fast-growing microbial cultures. Modified single-use bioreactors have been used, but are not designed for ideal growth conditions,” said Daniel Nelson, product manager, single-use systems at Thermo Fisher Scientific. “Through engineering an innovative, single-use exhaust and condenser system, coupled with powerful mixing, we overcame constraints in oxygen transfer to create the first purpose-built single-use fermentor. The HyPerforma SUF is a natural progression developed specifically for fermentation processes and a dedicated tool needed to increase choice, flexibility and performance for all bioprocessing workflows.”
Key product features include:
• Effective mass transfer, powerful mixing, and temperature control using three Rushton-style impellers and baffled, jacketed vessel
• 5:1 turndown ratio and 3:1 height-to-diameter ratio for consistent scalability and flexibility of process design (both 30 L and 300 L models).
• Efficient exhaust management system, enabling high flow rates (2VVM)
• Vertical access door for easy loading and retrieval of the bioprocess containers and harvest lines.
• Turn-around times between batches as low as 2 hours.
As a two-part product, the HyPerforma SUF comes paired with a Thermo Scientific BioProcess Container (BPC) — pre-sterilised and gamma irradiated. With an open architecture design, the HyPerforma SUF with BPC is highly flexible. It can also be retrofitted into existing fermentor operations, as well as configured to operate with existing software and control equipment, or delivered turnkey for immediate use.
Related News
-
News Eli Lilly gets ready to launch five new drugs in 2023
Eli Lilly, the American pharmaceutical company (IN, USA) are gearing up for a big year ahead, with hopes to launch five new drugs and capitalise on growing obesity and Alzheimer’s disease markets. -
News Amgen buys Horizon for $27.8 billion in bold step into the rare disease market
Amgen Inc buys pharmaceutical company Horizon Therapeutics in a multibillion-dollar deal, in hopes to capitalise on it's portfolio of drugs in the highly sort after rare disease market. -
News Pharma Supply Chain People Moves
The latest appointments and promotions across the pharmaceutical supply chain. -
News Merck to donate new Ebola vaccine to defend against outbreaks in Uganda
Pharmaceutical giant Merck has announced they will be speeding up the processing of a new vaccine against the latest strain of the Ebola virus, to be donated to a global non-profit organisation for distribution -
News CPHI Podcast Series: Driving innovation with pharmaceutical startups
The latest episode in the CPHI Podcast Series explores how startups are driving innovation by taking high-risk approaches and doing business with greater agility. -
News Greener and efficient processes: Quaternary Ammonium Salts
Quaternary Ammonium Salts play a crucial part in Organic Chemistry processes at many major industries. Discover why.
-
News Biosimilars save patients $11B annually, but barriers to adoption remain in US market
Biosimilars introduce competition into the biologics market, driving down prices and increasing patient access. -
News WHO recommends use of two monoclonal antibody treatments against Ebola
The health body recommended use of treatments by Regeneron and Ridgeback Bio
Position your company at the heart of the global Pharma industry with a CPHI Online membership
-
Your products and solutions visible to thousands of visitors within the largest Pharma marketplace
-
Generate high-quality, engaged leads for your business, all year round
-
Promote your business as the industry’s thought-leader by hosting your reports, brochures and videos within your profile
-
Your company’s profile boosted at all participating CPHI events
-
An easy-to-use platform with a detailed dashboard showing your leads and performance