Research & Development News
Research & Development news
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News MSDC Receives Funding for Alzheimer's Drug Study
The study will evaluate the safety profile and effects of the drug on brain glucose use in patients aged 55-85 with mild Alzheimer's disease. -
News Sinapis Pharma Completes Phase I Trial for Brain Injury Treatment
The trial successfully demonstrated the safety of an IV infusion of Methamphetamine and produced the IV infusion pharmacokinetics needed to initiate Phase IIa clinical studies in stroke patients. -
News Vitamin D Insufficiency Prevalent among Psoriatic Arthritis Patients
A new research reports a high prevalence of vitamin D insufficiency and deficiency among patients with psoriatic arthritis. -
News BioLineRx Enrols First Patient for Neuropathic Drug Phase I Study
The study will evaluate the safety, tolerability and pharmacokinetics of single or multiple doses of BL-1021 in healthy volunteers. -
News Pfizer Reports Positive Results of Lyrica Study
The study enrolled 501 subjects and demonstrated a reduction in endpoint mean pain score compared to a placebo. -
News Research Could Use Synthetic Tissue to Perform Drug Tests
A study has produced a synthetic tissue, a hydrogel, which mimics the properties of mucosal tissues, such as those found in the mouth and stomach, to assess how medicines will react in the body. -
News Nuvilex Reports Successful Breast Cancer Preclinical Studies
Nuvilex announced successful results for the treatment of breast cancer from preclinical studies. -
News Enzo Discover Novel Target for Metabolic Bone Disease
Enzo Biochem reported its discovery of new class of proteins to inhibit the Wnt signalling pathway. -
News Study Shows Talactoferrin Effective for Sepsis
The study evaluated 190 patients and showed talactoferrin reduced mortality and was well-tolerated in patients with severe sepsis. -
News Scientists Develops New Tech to Target Antibiotic Resistant Bacteria
Scientists believe the new technique will help under-used antibiotic drugs like colistin to be used to fight against the spread of life-threatening bacterial infections. -
News Sanofi Signs Antibiotics Research Collaboration Deal
Sanofi signs a research collaboration with Rib-X Pharmaceuticals to develop novel antibiotics. -
News Amgen & UCB to Conduct Sclerostin Antibody Test in NASA Shuttle
Amgen and UCB are working with NASA Ames Research Center to conduct a preclinical test of a sclerostin antibody in an experiment aboard space shuttle Atlantis. -
News Ataluren Proven Effective for Cystic Fibrosis
The trial enrolled 19 patients and showed ataluren induced improvements in chloride channel activity, cystic fibrosis-related cough and positive trends in lung function. -
News Pharmasset & Tibotec to Conduct Combination Study in Chronic HCV
The companies will test Pharmasset's PSI-7977, a nucleotide polymerase inhibitor, along with TMC435, Tibotecs protease inhibitor. -
News Study: Anti-smoking Drug Chantix Increases Heart Attack Risk
The study said the risk increased by 72 percent for healthy, middle-aged smokers. FDA officials responded by saying that more analysis was needed before the agency would change its position. -
News Almac to Perform Analytics for Alzheimer's Test
Almacs Diagnostics unit will be the central service lab to perform the analytic phase and results delivery to clinicians of Exonhit's AclarusDx diagnostic test. -
News Zalicus Starts Phase IIb Trial of Rheumatoid Arthritis Drug
The trial will evaluate the safety and efficacy of Synavive as a treatment for the signs and symptoms of rheumatoid arthritis in about 250 subjects. -
News Lucentis Proven Effective for Diabetic Macular Oedema
Genentech has announced successful clinical results from the two Phase III trials of Lucentis against diabetic macular oedema. -
News Scancell Develops New Vaccine against Lung Cancer
The vaccine, known as SCIB2, stimulates immune responses to the lung cancer antigen NY-ESO-1 and may also have potential utility in oesophageal, liver, gastric, prostate, ovarian and bladder cancers. -
News Type 1 Diabetes Vaccine Fails Trial
The researchers believe the vaccine could be used as part of a combination therapy to recent-onset type 1 diabetes patients. -
News Mimetogen Reports Positive Data for Dry Eye Treatment
The study included 150 patients and demonstrated improvements in signs and symptoms with its low and high doses of MIM-D3. -
News Bayer Advances Research for Pulmonary Hypertension
Bayer HealthCare works with the Ludwig Boltzmann Institute (LBI) for Lung Vascular Research in the research area of lung vascular diseases. -
News Scynexis & Anacor Report Positive Results for Sleeping Sickness Drug
The studies demonstrated the drug's safety and its ability to cross the blood-brain barrier, proving it effective against the disease in its first two stages. -
News TAK-875 Found Effective Against Type 2 Diabetes
The study results found that all doses of the drug showed glycosylated haemoglobin reductions at week 12 versus placebo. -
News Anacor Announces Positive Results of AN2728 for Psoriasis
Anacor Pharmaceuticals reports positive results from a mid-stage trial of a drug candidate designed to treat the skin condition psoriasis. -
News Sanofi & Weill Cornell Medical College to Discover New Anti-infectives
Under the terms of the collaboration, Sanofi will provide 80,000 chemical compounds to Weill Cornell, where the compounds will be screened to assess their ability to inhibit growth of Mycobacterium tuberculosis. -
News Study: India's R&D Needs Drug Collaborations
A new survey says Indian companies will need to start doing more collaborative work to catch up with trend setters in Eastern Europe. -
News Arno's AR-67 Shows Efficacy in Glioblastoma Multiforme Trial
The open-label and multicentre trial enrolled 16 patients and showed the efficacy of the brain cancer drug. -
News Altor and Florida Biologix in Cancer Therapy Pact
ALT-803 has demonstrated anti-tumor activities in various preclinical cancer models and could potentially make a life-changing difference for patients with solid and hematological tumors. -
News Isogenica, Biolauncher, Cresset in Discovery Platform Pact
The parties will integrate their expertise to identify active compounds against high-value therapeutic targets. -
News Roche Sets up R&D Institute in France
The Institute will serve as the single entry point for academic collaborations in France across multiple disease areas and scientific disciplines. -
News Lipid Reports Positive Results of Ulcerative Colitis Drug Tests
The study demonstrated the efficacy and safety of the drug in patients with mesalazine-refractory ulcerative colitis. -
News BMS & AstraZeneca Reports Positive Data for Diabetes Treatment
BMS and AstraZeneca reported positive data from a Phase III clinical study evaluating their investigational sodium-glucose co-transporter-2 (SGLT2) inhibitor dapagliflozin, combined with metformin, for the treatment of type 2 diabetes. -
News Leukothera Combined with Other Agents Enhances Anti-Leukemia Effects
Recent findings showed when combined with standard anti-leukemia agents, the biological activity of a drug candidate showed synergistic anti-leukemia effects. -
News Life Technologies to Develop DNA Sequencing Test for Tumours
Beyond providing a platform to develop new drugs, the genomic test will also bring significant economic benefit to the UK, as it will be commercially available to a global market. -
News Redx Pharma Bids for Cancer Research Funding
The ?5.9m grant will help the company fund a two-year research project. -
News Drug Side Effect Linked With Increased Health Risks for Over 65
The study is the first systematic investigation into the long term health impacts of 'anticholinergic activity'. -
News Porsolt and JSW Sign Research Services Deal
Porsolt and JSW announced that they have signed a strategic collaboration agreement to co-market complementary contract research services. -
News Scientists Develop New Cystic Fibrosis Drug
The study found a significant improvement in lung function and a reduction in disease flare-ups in those receiving the treatment. -
News CorMedix Completes Patient Enrolment in Kidney Disease Study
CorMedix announced its completion of patient enrollment in its Phase II contrast-induced acute injury study with its oral drug candidate CRMD001. -
News CytRx Reports Positive Results of Bafetinib in Leukaemia Patients
CytRx announced the preliminary results from its Phase II trial of cancer-inhibitor candidate bafetinib. -
News Adcetris Proven Effective in Hodgkin Lymphoma Patients
The findings indicated the drug benifitted patients for whom standard second-line induction therapy is not an option or has failed to produce a robust response prior to autologous stem cell transplant. -
News Rozrolimupab Shows Efficacy in Immune Thrombocytopenia Patients
Symphogen has reported the preliminary results from a Phase II clinical trial of rozrolimupab in RhD positive, non-splenectomised adults with immune thrombocytopenia. -
News Vertex Reports Interim Results of Cystic Fibrosis Combination Therapy
The first part of the study demonstrated the safety and tolerability of the combination regimen with no serious side effects. -
News Abbott Reports Positive Results from Parkinson's Drug Trial
Drug developer Abbott has reported interim efficacy and safety results from a Phase III study of levodopa-carbidopa intestinal gel. -
News Sanofi's Dengue Fever Vaccine Makes Progress in Thai Trial
The vaccine, which could be the first vaccine for dengue fever, is on track to be available in 2014. It is being tested in 15 countries and initial results are expected at the end of next year. -
News US Researchers Complete Study on Nerve Agent Treatment
Researchers have completed a Phase I study with atropine sulphate delivered from a MicroDose proprietary dry powder inhaler to combat the effects of nerve agent poisoning. -
News Merck & Intercell End MRSA Vax-Trial
The decision to terminate was based on the observation that V710 was unlikely to demonstrate a statistically significant clinical benefit. -
News Roche & Merck to Develop Cancer Diagnostic Tests
This collaboration provides Merck with access to diverse developmental and commercial diagnostic technologies. -
News Scientists Launch Vaccine Research Foundation
The Foundation's activities will focus on persuading opinion leaders, policymakers inside and outside government, and other decision makers of the benefits and safety of vaccines and the merits of increased investment in vaccine research. -
News Pfizer Conducts First 'Virtual' Clinical Trial
The pilot project, initiated following review from the U.S. FDA, uses mobile phone and web-based technology to collect necessary data for the trial without clinic visits. -
News Ganetespib Receives Positive Phase II Trial Results
Synta Pharmaceuticals has announced successful clinical responses from the Phase II trial of ganetespib in patients with advanced non-small cell lung cancer. -
News Relovair Shows Efficacy for COPD
The drug showed reduction of exacerbations and improvements in lung function. The study also demonstrated the safety and efficacy of the drug candidate for COPD. -
News Teva Completes Patient Enrolment for Multiple Sclerosis Trial
The Phase III trial is designed to examine the efficacy, safety and tolerability of the drug versus a placebo. -
News Lymphoma Vaccine Extends Survival in Late-stage Study
The study continues to show that the vaccine increases the usual time until relapse for follicular lymphoma by about 14 months. -
News BioSante Completes Patient Enrolment in LibiGel Study
BioSante Pharmaceutical said the ability to top enrolment as per the sample size analysis indicates a 90% predictive probability of success of the LibiGel Phase III clinical development programme. -
News DPX-0907 Cancer Vaccine Successful in Phase I Trial
The trial was conducted at five centres in the US, and evaluated the safety and immunogenicity of DPX-0907 vaccine in patients with advanced stage breast, ovarian or prostate cancer. -
News Tigris Starts Randomized Phase 2 Study of AFP-464
The primary endpoint of the study is to determine the percentage of patients that achieve a Clinical Benefit Response. -
News Lilly's Study: Cixutumumab Effective in Five Sarcoma Subtypes
The Phase II trial included 113 patients demonstrated that 57% of patients taking cixutumumab experienced stable disease. -
News Tigris Starts Randomized Phase 2 Study of AFP-464
The primary endpoint of the study is to determine the percentage of patients that achieve a Clinical Benefit Response. -
News AstraZeneca and Heptares Collaborate for Drug Discovery
Under the terms of the agreement, AstraZeneca has worldwide commercial rights to product candidates emerging from the collaboration. -
News NLX-P101 Proven Effective Against Parkinson's
The results demonstrated that treatment with gene therapy agent showed the clinically meaningful improvement and durability over the long-term. -
News Basilea Reports Positive Results of Antibiotic BAL30072
Basilea Pharmaceutica reported positive top-line results from the Phase I study of its antibiotic BAL30072. -
News Sanofi and DNDi Sign Research Collaboration Agreement
In the framework of this agreement, Sanofi will initially bring molecules from its libraries into the partnership, while DNDi and Sanofi collaborate in research activities on innovative molecular scaffolds. -
News Novartis Announces Positive Results from ACZ885 Drug Studies
Novartis recently announced positive data from two late stage trials of its pipeline candidate ACZ885 for the treatment of patients suffering from severe gouty arthritis. -
News Basilea Reports Positive Results from Antibiotic BAL30072 Study
The clinical phase I study investigated the safety, tolerability and pharmacokinetics of single ascending doses of BAL30072 in healthy volunteers. -
News KemPharm Drug KP201 Proven to Relieve Pain
KemPharm announced positive results from a Phase 1 clinical trial of its most advanced opioid-based drug candidate, KP201, a novel hydrocodone prodrug for treating pain. -
News Tribenzor Proven Effective for Hypertension
The Phase III study included 2,492 patients and showed Tribenzor was safe and effective in patients with hypertension. -
News Combination of Two Common Medications May Increase Blood Glucose Levels
The increase is more pronounced in people who are diabetic, and in whom the control of blood sugar levels is particularly important. -
News TMC435 Proven Effective for Hepatitis C
Medivir announces positive 48-week interim data from TMC435 hepatitis C Phase IIb study. -
News CT-011 Lymphoma Drug Shows Positive Phase II Results
The study showed that the drug increased the number of specific T-cells responsible for the maintenance of long-term immunologic memory. -
News Xgeva Prostate Cancer Drug Reports Positive Phase III Results
The Phase III study showed the drug increased bone metastasis-free survival for more than four months, delayed the time to first bone metastasis and reduced risk by 15% compared with the placebo. -
News Exagen and Medco Start Program to Aid in Personalized RA Treatment
The study aims to understand how methotrexate is being absorbed, retained, and metabolized by a patient. -
News Study Finds Gene Warning of Alzheimer's before Symptoms Onset
A gene allele that increases the risk of Alzheimer's disease starts to damage the brain 50 years before symptoms of the disease appear, a new study says. -
News Researchers: Anti-Retroviral Drugs Cut HIV Deaths by 60% in China
Researchers have announced that anti-retroviral drugs have cut deaths caused by HIV by more than 60% in China. -
News NovaBay Reports Positive Results of Ophthalmic Solution
NovaBay Pharmaceuticals announced the results of a phase II clinical study for the treatment of adenoviral conjunctivitis. -
News AstraZeneca's Olaparib Shows Promise in Ovarian Cancer
AstraZeneca said the results may have a positive effect on progression-free survival in women with serous ovarian cancer, and may be a therapeutic option for the aggressive form of cancer. -
News UK Invests in Personalised Medical Projects
The UKs Technology Strategy Board and the Medical Research Council are jointly investing ?3.7m in seven major research projects for personalised medicine. -
News Takeda and Lundbeck Initiate Major Depressive Disorder Drug Trial
Takeda and H Lundbeck announced the initiation of a phase III clinical trial in Japan for Lu AA21004 in patients with major depressive disorder. -
News Study Sheds Light on Disabling Human Mitochondrial Disorders
The current study focused on an inherited genetic deficiency that prevents the production of coenzyme Q, a critical antioxidant and component of the energy-generating respiratory chain. -
News Lilly Presents Data on Cixutumumab in Five Subtypes of Sarcoma
This trial assessed progression-free survival as a primary endpoint in 113 patients with advanced or metastatic soft tissue sarcoma and Ewing family of tumors who were treated with cixutumumab. -
News UK Clinical Trial Network to Launch to Fight Blood Cancer
A network of clinical trial centres will launch in the UK to improve survival rates among patients suffering from blood cancers. -
News AstraZeneca Inhalation Aerosol Effective for Asthma Patients
The data from the Symbicort study supports the understanding of the product's efficacy and safety in African-American patients, who are more prone to asthma. -
News Pacira Pain Drug Exparel Reports Positive Results
The study included 189 patients and showed that 94.7% of patients treated with Exparel were satisfied with their post-surgical analgesia. -
News Abbott's Humira Effective Against Ulcerative Colitis
Abbott has submitted applications to both the US Food and Drug Administration and the European Medicines Agency seeking approval to market Humira. -
News GSK and AstraZeneca Announce Inflammation Research Collaboration
The Manchester Collaborative Centre for Inflammation Research will bring together scientists from the pharmaceutical industry and academia to work on inflammation research and translational medicine. -
News Pharma Research Projects Compete for 1Bn Funding Pots
The European Commission has selected two research projects in a shortlist of six that will compete for two EU funding agreements, each worth 1bn. -
News EU Research to Boost Utility of Alternative Medicine
The CAMbrella project aims to develop a European research plan boosting the utility of alternative medicine, and to help to develop regulation. -
News Halozyme & ViroPharma to Develop Subcutaneous Cinryze
Under the agreement, Halozyme may receive as much as $83 million, with $9 million upfront and potential future milestone payments of $74 million based on clinical and regulatory targets, plus a 10% royalty on future sales. -
News Nexvax2 Proven Effective for Coeliac Disease
The study demonstrated the effect of weekly injections of Nexvax2 over three weeks, in coeliac patients on a strict gluten-free diet. -
News Study Demonstrates Velcade's Effectiveness Against Multiple Myeloma
The results showed that 45% of patients in the Velcade arm achieved a complete response or near complete response, compared to 35% of patients in the control group. -
News Abbott's HUMIRA Study Meets Primary Endpoints
The study analysis included 494 adult patients with UC who had not responded well to conventional therapy. -
News Pfizer Receives Positive Results for Menopause Drug Pristiq
Pfizer has published clinical trial data that supports the effectiveness of its drug Pristiq for the treatment of hot flashes in postmenopausal women. -
News Pfizers Prevnar 13 Meets Phase III Endpoints
Pfizer announced that its Phase 3 immunogenicity and safety trials of Prevnar 13 in adults aged 50 years and older have met all study endpoints. -
News Kancera to Battle Aggressive Cancer
The Swedish firm will collaborate with a research group to deliver novel therapies aimed at overcoming drug resistance and relapse in cancer. -
News Research Agreement to Develop New Drugs against Diarrhea
The collaboration between the Center for World Health and Medicine and the Institute for OneWorld Health aims to develop safe and effective anti-secretory drugs. -
News Study: Amira AM152 Proven Effective
The Phase I clinical study in healthy volunteers showed that AM152 is safe and well-tolerated at doses that are expected to provide a full range of receptor coverage in humans. -
News DNA from Common Stomach Bacteria Minimizes Effects of Colitis
A study shows DNA from Helicobacter pylori, a common stomach bacteria, minimizes the effects of colitis. -
News Insight Into HIV Immunity May Lead to Vaccine
The research group analysed blood samples of people with HIV and found their virus had evolved to evade or escape the ADCC antibodies against HIV they are making to try to control their virus. -
News HIV Drug Could Prevent Cervical Cancer
Lopinavir, a widely used HIV drug, could be used to prevent cervical cancer, scientists have found. -
News SARcode Announces Positive Clinical Results of Dry Eye Treatment
SARcode Corporation presented study results for their lead investigational molecule, SAR 1118. -
News Roche Study Disputes Positive Avastin Report
Initial findings of the analysis of 78,000 Medicare patients indicated that there was an 11% greater chance of death and 57% higher chance of stroke among those taking Avastin compared to those taking Lucentis. -
News Selexys Pharmaceuticals Initiates Enrollment in Phase I Clinical Study of SelG1
This study will evaluate the safety and pharmacology of SelG1 prior to advancement into a Phase II trial in patients with sickle cell disease. -
News Icagen & Pfizer Enter Research Pact With Yale
A three-party collaboration deal has been achieved among the Yale School of Medicine, Pfizer, Inc. and Icagen, Inc. to investigate potential new pain compounds. -
News PolyMedix PMX-30063 Effective Against NDM-1 Drug-Resistant Bacteria
The drug candidate is currently undergoing Phase II trial in patients with acute bacterial skin and skin structure infections that are caused by Staphylococcus bacteria. -
News Plant Extract Offers Improved Therapy for Hay Fever
Further studies need to be carried out in order to allow it to be sold as a prescription drug on the German market. -
News Thai Researchers Test Brain Cancer Delivery System
Thai researchers from Mahidol University gave their focus on a new drug-delivery system to treat brain cancer patients. -
News MonoSol Rx & KemPharm to Jointly Develop ADHD Drug
MonoSol Rx and KemPharm have partnered to jointly develop KemPharm's KP106 for ADHD patients. -
News Selumetinib Shows Positive Results Against Biliary Cancer in Phase II Trial
A Phase II clinical trial has demonstrated positive effects of selumetinib in people with advanced biliary cancer. -
News BioAlliance Pharma Accelerates Clinical Development of Clonidine Lauriad
The expansion of the trial to two new European countries will raise the total number of centers to over 40 and will help accelerate patient recruitment. -
News New Biomarkers Study Could Lead to Better Malaria Vaccine Design
The goal of the study is to identify and validate biomarkers that correlate with vaccine-induced protective immunity against malaria infection. -
News Study: Anti-Inflammatory Drugs Reduce Antidepressant Efficacy
In the absence of anti-inflammatory drugs, 54% of patients responded to the antidepressant, whereas only 40% of patients responded in the presence of anti-inflammatory agents. -
News Hepatitis B Virus Reemerges with Long-term Nucleoside Analog Treatment
Results showed that during a mean follow-up of 38 months, 39 (26 percent) of patients had at least one VBT, and upon retesting, 38 percent of these patients did not have a VBT and 10 (38 percent) had no evidence of genotypic resistance. -
News Study Shows Promise For Developing Protein Therapies For Disease Prevention
Understanding the role of protein molecules is vital for health research and finding cures and medicines for diseases. -
News Biovista Inks Research Collaboration Agreement with Novartis
Biovista announced that it has entered into a research collaboration agreement with Novartis. -
News Phase III Trial of Hyperphosphatemia Drug Begins in Japan
Japan Tobacco and Torii Pharmaceutical have started the Phase III clinical trial of ferric citrate in Japan to treat patients with hyperphosphatemia. -
News New Solution Found for Cystic Fibrosis Infections
Researchers found a new way to deal with cystic fibrosis infections. -
News Researchers: New Pain Drug Tastes Awful
Pain Therapeutics is out to develop a more abuse-resistant drug that includes oxycodone, a very effective painkiller which has proven to be very easy to abuse in the past. -
News Scientists: Anti-Inflammatory Drugs Reduce Effectiveness of SSRI Antidepressants
This discovery may explain why so many depressed patients taking SSRIs do not respond to antidepressant treatment. -
News First Patient Enrolled in Phase 2 Clinical Study of HQK-1001 in Patients With Sickle Cell Disease
HemaQuest said clinical investigators have enrolled the first patient in a randomized multi-dose Phase 2 study of HQK-1001 in patients with sickle cell disease.
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