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16 Mar 2011

Once-Monthly Injectable Exenatide Improves Glucose Control in Study

The study evaluated the efficacy, safety and tolerability of three doses of exenatide once-monthly.

Amylin Pharmaceuticals, Eli Lilly and Alkermes have reported positive results from a Phase II study that evaluated the effect of a once-monthly injectable suspension formulation of exenatide on glycaemia control in patients with type 2 diabetes.

 

The randomised and open-label study evaluated the efficacy, safety and tolerability of three doses of exenatide once-monthly. It also evaluated once-weekly doses of exenatide extended-release for injectable suspension (proposed brand name Bydureon), another investigational type 2 diabetes therapy.

 

The study enrolled 121 adults who were randomised to receive 2mg weekly subcutaneous injections of Bydureon or subcutaneous injections of exenatide once-monthly at a low,

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