12 Jun 2024

The Lonza Engine™ Alliance Program

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Our capsule filling equipment partnership program allows customers to match the best equipment for their process with the high-quality and performance of Capsugel®️ capsules.

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Lonza Capsules & Health Ingredients

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  • 2015
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Other Content from Lonza Capsules & Health Ingredients (18)

  • News On track at CPHI Barcelona - The Track Sponsor interview: Lonza

    In our packed out content sessions at CPHI Barcelona this year we focus on some of the hottest topics coming up in the pharma industry, with each track sponsored by a leading expert in the field. 
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    Dry-powder inhalation (DPI) technology offers a favorable drug development opportunity for respiratory or systemic drug delivery. Delivering a uniform dose in a portable, easy-to-use system, capsule-based DPI devices are a simple and cost-effective way to deliver inhalable medication. Capsugel® Zephyr™ is Lonza’s customizable dry-powder inhalation capsule portfolio that is optimized to provide superior performance and compatibility between the capsule/device and capsule/formulation.
  • News The Top 5 Industry Content Reads on CPHI Online

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    The Company Showcase profiles offer a library of free to access, downloadable content, including videos and webinars, reports, whitepapers and product brochures, from the Pharma suppliers and service providers you’d look to meet at our events.

  • Brochure Launch with Lonza™️ innovation services

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  • Video Improve Drug Delivery with Capsule Formulations

    In this webinar, formulation scientists and pharmaceutical development specialists will learn how Lonza’s Capsule Applications Services lab can address drug solubility limitations, develop innovative capsules to tailor drug delivery, and optimize encapsulation processes.

    Click here to register

  • Video Making a Splash in the US Market: How PBPK Modeling is Playing a Central Role in Risk Reduction

    Rapid and efficient development of drug candidates is increasingly important for pharmaceutical companies with accelerated timelines and funding constraints. However, many early drug candidates have poor oral absorption properties making it challenging to achieve target pharmacokinetic (PK) profiles. Without upfront knowledge of absorption risks and mitigation strategies, poor absorption can significantly impact preclinical and clinical study timelines and costs. Physiologically-based pharmacokinetic (PBPK) modeling software, such as the GastroPlus® platform from Simulations Plus, simulates dynamic physiological factors impacting oral performance. When coupled with in vitro measurements, PBPK modeling is effective in early development for 1) identifying absorption risks, 2) assessing the potential for solubility enhancing formulations such as salts, cocrystals, or amorphous solid dispersions to mitigate these risks, and 3) designing and optimizing preclinical and clinical studies with respect to dose, prandial state, or gastric pH modification to maximize the likelihood of achieving desired PK profiles. In this presentation, we will demonstrate how PBPK models combined with Lonza’s custom and off-the shelf in vitro tools and solubility enhancement expertise can be used to identify and mitigate absorption risks in early drug development, reducing the need for drug product reformulation or repeated preclinical or clinical studies. Key Learning Objectives: Learn how PBPK modeling can identify potential oral absorption risks and mitigation strategies (e.g. bioavailability enhancement) for early drug candidates. Learn how PBPK modeling coupled with in vitro testing can guide early selection of drug form and formulation to achieve clinical study goals. Gain insights into how key drug and formulation factors including solubility, permeability, and dissolution rate can impact absorption risks such as poor oral bioavailability, food-drug interactions, and pH-dependent DDI effects.
  • Video The Benefits of the Next Generation Enteric Capsugel® Capsule for your Future Product Development

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    This solution is supported by scientific studies, both in-vitro and in-vivo, showing that enteric protection and targeted delivery to the distal intestine are achieved in comparison to marketed references.

    Backed up also by performance studies, this capsule showcases excellent machineability and mechanical properties, in line with standard immediate release HPMC capsules. It is available commercially in large quantities.

    Join Dr. Vincent Jannin to learn more on the newly launched enteric solution.
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    David Erritzøe is an Honorary Clinical Research Fellow at Imperial College London and researches using psychedelics for clinical psychiatric purposes. Due to the history of psychedelics, the subject of David and his team seems a bit controversial. But the research area is blossoming, and the interest in the field is higher than it has been in many years.

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  • Video The Application of EXCiPACT GMP Standard To Pharmaceutical Auxiliary Materials

    EXCiPACT is extending its certification scheme to PAMs and is developing a guide for manufacturers and auditors.

    As these materials may be in intimate contact with a material which will be administered to patients, they should be manufactured in accordance with GMP principles. Typically, PAMs are removed before use in the manufacture of a drug product or function as processing aids in the manufacture of the excipient.

    Although the manufacturing processes used for PAMs may not be traditional chemical manufacturing processes, applying the risk-based approach in EXCiPACT GMP means this standard can be applied to PAMs. The guide will help manufacturers apply EXCiPACT GMP to the preparation and distribution of PAMs and auditors to assess their compliance for certification purposes.
  • Video Lessons from the Future: Cannabis and Psychedelic Industries

    With North America’s recent embrace of the emerging cannabis and psychedelic industries, there are countless lessons to be learned about how to operate in such an exciting and challenging field. This international and scientifically diverse panel will discuss their cannabis and psychedelic experience in North America to help bolster and harmonize European advancements.

    These speakers will share a transatlantic perspective in these emerging medical markets with examples that encompass all aspects of the product development pipeline. Regional specific development challenges, including differences in market preferences, will be highlighted.
  • Video Oral Solid Dose Innovation

    This session was originally broadcast as part of the CPHI Worldwide 2021 digital content programme. Forefront Key Formulation Variables & Approaches Formulation Development of Complex Oral Dosage Forms Discuss innovations & emergence of advanced technologies (e.g., 3D Printing) Main Driver and Areas of Growth for Oral-Dose Outsourcing Patient-Centric Innovation
  • Video The Importance of Colours and Why it Matters in the Pharmaceutical Market

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  • Video Value Added Excipients to Unlock the Potential of APIs

    This webinar originally aired as part of CPHI Discover - 17-28 May 2021 The humble excipient can play an important role in improving drug formulation, particularly in terms of solubility and stability. This session will explore how to add value to your drug development. Discussion points: The Vital Role Excipients play in producing new drugs and consumer products. An overview of Excipient Quality and Impact on Formulation Excipients Added to Solid Oral Dosage Forms to Improve Drug Solubility and/or Dissolution Latest Developments, demands & trends in the Excipients Market Examples of some Solutions, technologies, and regulatory changes happening on a global scale
  • Video Drug Delivery & Development: Overcoming Tomorrow’s Formulation Challenges

    This panel aims to provide an overview of the latest approaches to formulation and process challenges for drug development, manufacturing and supply, Highlighting a customized approach to optimize the performance of the end product. Our expert panel members will be sharing their views and experiences on the following key topics: Dry-powder inhalation (DPI) technology for favourable drug development and as a cost-effective and straightforward way to deliver inhalable medication, Drug Delivery Technologies for Women's Health Applications and 3D printing technologies reshaping drug discovery and pharmaceutical development and manufacturing. This presentation was originally aired as part of the CPHI Festival of Pharma.