Peptide lead optimization

Peptide lead optimization
Product Description

Increasing peptide drug potency and improving pharmacokinetic properties through lead optimization of linear and CLIPS-constrained peptides -
We have developed a diverse library of enhanced CLIPS molecules, which after incorporation can lead to improved peptide conformation as well as better pharmacokinetic properties. This addition directly affects the potency of lead drug candidates, for example through:

  • improved specificity,
  • complex stability, and
  • decreased elimination/clearance.
Pepscan’s scientists build on over 25 years of experience. Our highly skilled project teams combine chemistry and biology expertise and are well-equipped to bring a peptide lead drug candidate to the next level.

Pepscan

  • NL
  • 2021
    On CPHI since
  • 25 - 49
    Employees
Company types
Manufacturer/Innovator

Pepscan

  • NL
  • 2021
    On CPHI since
  • 25 - 49
    Employees
Company types
Manufacturer/Innovator

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Pepscan resources (2)

  • News Pepscan supports Ardigen ImmuMap research collaboration with its neoantigen peptide synthesis capabilities

    Pepscan will use its 25 years of experience in peptide synthesis to deliver large quantities of custom neoantigen peptides to the research collaboration between Ardigen and Immumap. ImmuMap will perform the experimental validation of T-cell receptors towards newly identified neoantigens of solid-tumor patients using Pepscan’s neoantigen peptides. The outcome will accelerate Ardigen’s TCR-based therapy discovery and development using artificial intelligence.
  • Brochure Pepscan - Enabling life-improving breakthroughs by mastering peptides

    Combining smart peptide science and flexible manufacturing capabilities conform GMP - Over the last few years, we have made tremendous efforts and investments in building our GMP capabilities at our Dutch all-in-one facility. Starting from GMP production of neoantigen vaccines at microgram scale, we have rapidly expanded to GMP production at gram scale, building on our 25-year track record in peptides. This has also increased our flexibility so we can deliver batches based on our customers’ timelines.