PolyCrystalLine S.p.A

About PolyCrystalLine S.p.A

Since 2005 PolyCrystalline provides reliable solutions to optimise and control the crystallisation process of Active Pharmaceutical Ingredients for pharmaceutical companies. Our mission is to support our clients during drug development, helping them to reduce batch failure, avoiding costly crystallisation issues and overall offering greater confidence in drug quality during manufacturing. We can support you from early-phase drug discovery to kilogram supply. We are a high performing cohesive team of trained chemists and analysts, with more than 15 years of experience in the development and optimization of APIs crystallization. We care about results and innovation based on sound science and the use of modern technologies.

Certifications
  • IT
  • 2015
    On CPhI since
  • 2
    Certificates
  • 25 - 49
    Employees
Contract Service
Contact info

Products from PolyCrystalLine S.p.A

  • Amorphous Dispersion

    Product Amorphous Dispersion

    PolyCrystalLine offers a wide range of solid form screening which includes amorphous dispersion. Its arrangement. Although the amorphous form is the most soluble form, it exhibits the lowest stability. Amorphous compounds are produced in the conditions when precipitation is kinetically faster than crystallisation and crystalline disorder caused by processing (i.e. Milling or micronisation). Contact us for more information.
  • Analysis Of Water Content

    Product Analysis Of Water Content

    PolyCrystalLine offers a wide range of analytical services which includes analysis of water content. It is essential to know the amount of water contained in the individual active ingredients and excipients of a drug in order to correctly predict its lifetime, stability and effectiveness. Contact us for more information.
  • Api-Excipient Compatibility Studies

    Product Api-Excipient Compatibility Studies

    PolyCrystalLine offers a wide range of Pre-formulation studies which includes API-excipient compatibility studies. It contains excipients which can affect the chemical, physical and therapeutical properties, product stability and may even cause a change in the API polymorphic form. Its interactions is a crucial step in preformulation studies of drug development to achieve a robust and effective formulation of dosage forms that make administration easier, improve patient compliance, promote release and bioavailability of the drug and increase its shelf life. Contact us for more information.
  • Cgmp Quality Control

    Product Cgmp Quality Control

    PolyCrystalLine offers a wide range of analytical services which includes cgmp quality control. Its provide a full complement of state-of-the-art gmp analytical testing resources and expertise to support cgmp quality control testing for raw materials, active pharmaceutical ingredients (api) and intermediates. Contact us for more information.
  • Co-Crystals Screening

    Product Co-Crystals Screening

    PolyCrystalLine offers a wide range of solid form screening which includes co-crystals screening. It is an molecular crystals in which at least one of the compounds is an active pharmaceutical ingredient (api). Salts are considered different from co-crystals provided that its crystals formed by ionic multicomponent. Contact us for more information.
  • custom synthesis

    Product custom synthesis

    Api and impurities
  • Dissolution Testing

    Product Dissolution Testing

    PolyCrystalLine offers a wide range of Pre-formulation studies which includes Dissolution testing. It is a Drug absorption from a solid dosage form after oral administration depends on the release of the drug substance from the drug product, the dissolution or solubilisation of the drug under physiological conditions, and the permeability across the gastrointestinal tract. Contact us for more information.
  • In Vitro Bioequivalence Studies

    Product In Vitro Bioequivalence Studies

    PolyCrystalLine offers a wide range of Pre-formulation studies which includes In vitro bioequivalence studies. It is considered as a surrogate for clinical evaluation of the therapeutic equivalence of drug products based on the fundamental bioequivalence assumption that when two drug products are equivalent in bioavailability, they will reach the same therapeutic effect. Contact us for more information.
  • Kilo-Lab

    Product Kilo-Lab

    Kilo Lab, available for HPAPI, narcotic or controlled substances, pressure reactions
  • Method Development & Validation

    Product Method Development & Validation

    PolyCrystalLine offers a wide range of analytical services which includes method development & validation. It can be entrusted with the most sensitive projects for method development and validation of api’s intermediates, raw materials and finished products. Contact us for more information.
  • Physical Characterization

    Product Physical Characterization

    PolyCrystalLine offers a wide range of analytical services which includes physical characterization. Its an physicochemical properties of a compound is essential so that the formulation process can be rational and streamlined. Contact us for more information.
  • Polymorph Screening

    Product Polymorph Screening

    PolyCrystalLine offers a wide range of solid form screening which includes polymorph screening. In an early stage of drug development helps to avoid manufacturing problems, to fine-tune the performance of drugs and provides space for innovations. Contact us for more information.

PolyCrystalLine S.p.A Resources