Pregabalin

Pregabalin
Product Description

Pregabalin is a 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic, and analgesic activities. Although the exact mechanism of action is unknown, pregabalin selectively binds to alpha2delta (A2D) subunits of presynaptic voltage-dependent calciumchannels (VDCCs) located in the central nervous system (CNS). Binding of pregabalin to VDCC A2D subunits prevents calcium influx and the subsequent calcium-dependent release of various neurotransmitters, including glutamate, norepinephrine, serotonin, dopamine, and substance P, from the presynaptic nerve terminals of hyperexcited neurons; synaptic transmission is inhibited and neuronal excitability is diminished. Pregabalin does not bind directly to GABA-A or GABA-B receptors and does not alter GABA uptake or degradation.

CTX LifeSciences Pvt. Ltd.

  • IN
  • 2015
    On CPHI since
  • 4
    Certificates
  • 500 - 999
    Employees
Company types
CMO/CDMO
Manufacturer/Innovator
Pharmaceutical company
Primary activities
API Producer
Contract Manufacturer
Custom Manufacturing/Custom Synthesis
Fine Chemicals Company
Generic APIs producer
Intermediates Manufacturer
Specifications
  • CAS Registry Number
    148553-50-8
  • Supplied from
    India

CTX LifeSciences Pvt. Ltd.

  • IN
  • 2015
    On CPHI since
  • 4
    Certificates
  • 500 - 999
    Employees
Company types
CMO/CDMO
Manufacturer/Innovator
Pharmaceutical company
Primary activities
API Producer
Contract Manufacturer
Custom Manufacturing/Custom Synthesis
Fine Chemicals Company
Generic APIs producer
Intermediates Manufacturer

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CTX LifeSciences Pvt. Ltd. resources (1)

  • Video CTX Lifesciences - Your Preferred API, Intermediates Manufacturing & CDMO Partner from India.

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