Procaps SA

A unique oral dosage form that allows having tablets, capsules, granules or pellets inside a single, larger soft gelatin capsule. Unigel™ is the only patented technology for fixed dose combinations which incorporate the benefits of soft gelatin capsules. Created for patients and consumers who want more in one product, who want simplicity and effectiveness backed by technology and expertise when taking their meds and supplements.

What gets us excited about our Unigel technology:

·       Physically-appealing products
·       Clear visibility of the ingredients and dosage forms
·       Convenient
·       Different release-profiles
·       Multi-functional ingredients in one single dose
·       Different gelatin formulations (animal and non-animal)
·       Ideally suited for vegetarian and vegan diets​
·       Formulations with fewer artificial ingredients
·       Enables brand differentiation
Unigel can take your brand to the next level. Clear, Multi-functional, Smart and Effective. Unigel™ gives you the possibility of customizing your own and unique formula. Under this technology you can create your personal recipe with the ingredients you prefer for the specific target or market.

Discover our Chewable Softgel Platform ChewgelsTM, chewable soft capsules as a solution and line extension to existing or new products. With new ingredients, special shapes and flavors, we can offer our customers a range of formulations for different therapeutic lines. But, when thinking about consumers two words arise: needs and expectations. Talking about needs, chewable options offer a solution to difficulties in swallowing oral forms such as tablets or pills, ranging from children, seniors and patients with dysphagia. BUT, when Talking about expectations, we refer to a wide range of consumers looking for indulgent and different experiences in flavors, textures, natural and new/specialized ingredients, also including the curious generations of consumers demanding for unique and innovative products that tell a story.

Chewable soft capsules are soft, easy to swallow dosage forms that do not stick to the teeth nor leave any residues in the mouth. They offer a fast-oral release, taste masking and convenience since they´re easily taken w/o the need of water. There is a wide range of formulations for both chewable capsules and gummies, flavors, textures as well as functional ingredients. Particularly to CSC, they offer increased stability to APIs sensible to light or temperature and enhanced absorption of APIs formulated as emulsions.
Our chewgels technology is also:

·               Suitable for pharmaceutical compositions, nutraceuticals, vitamins, nutritional supplements, and similar products.
·               Extensively used USP excipients for improving the physical properties and texture of the soft capsules
·               Comprises at least one starch with a range from 0.1% to 35% of the total weight of the composition of the shell.
·               A gelatin that ranges from  20% to 60% of the total weight of the composition of the shell.Chewgels is an ideal solution for the Supplement category, including: 
·               immunity
·               Energy
·               Everyday Nutrition
·               bone health
·               Kid´s Health
·               Herbal Extracts
·               Sports Nutrition
·               Combinations Supplements
·       Omega-3’s

At Fun-trition we are focused on offering a complete experience in every bite of our delicious gummies. From Gelatin, to Plant-based technologies to guilt-free, sugar-free gummy formulations we understand that good nutrition doesn't have to be boring. At Funtritiom, we don’t just manufacture gummies, we create new products and ideas based on what you need. We give you the tools to get inspired and build a product of your own. We can develop and manufacture a one-of-a-kind nutraceutical gummy for your brand.

Our scientists are curious and experimental are constantly playing with the mixture of different hydrocolloids to obtain new products and target specific markets. We are able to mix the best of each gelling agent into a single gummy product.  Gummies made from various hydrocolloids such as agar, pectin, starch and carrageenan differ in textural and gel melting properties, offering new product development opportunities. We have developed several formulas with a mixture of hydrocolloids for different purposes in sensorial experiences and even to solve costs and technical issues: for instance, a mixture with starch to increase the melting point basically for countries where the ambient temperature is an issue.

Vegetarian softgels are becoming increasingly competitive with animal-based gels. ​As development efforts continue, additional areas of limitation may be overcome, such as the desire to use natural colorants and high-viscosity ingredients. ​ Meet our vegetarian softgel technology, VersagelTM, a versatile option for the encapsulation of high viscous, semisolid or high pH fill contents

Versagel capsules consumer benefits:​
·       Plant-based shell free of all animal derivatives​, well suited for consumers with dietary and religious or cultural restrictions
·       Ideal for consumers seeking products to fit their healthy lifestyles​
·       Gluten free and Sugar free​
·       Easy to swallow softgels 
·       Odor and taste free
·       Options available in variety of colors, shapes, sizes, and clarity​

We offer fully assistance for development, formula optimization, and encapsulation of CBD-THC products. Soft gelatin capsules are the ideal dosage form considering both bioavailability and stability of Cannabis medicinal products. Additionally, our unique and patenteted Unigel technology offers a unique platform for fixed dose combinations products with cannabis. 

Innovative Technologies to improve Therapeutic Adherence. Meet Gtabs, Gelatin Coated Tablets technology.  Gtabs is a Technology for tablets cotaed with gelatin, one or two tonedm, considered the best way to mask unpleasant odors and flavors, prevent counterfeiting and guarantee therapy adherence.
 
HIGHLIGHTS OF THE TECHNOLOGY

•        Guarantees better product stability
•        Effective protection for photosensitive pharmaceutical ingredients
•        Limits degradation due to poor exposure to air
•        Unique presentation: Difficult to imitate
•        Available in a variety of shapes and colors
•        G-Tabs allows satisfactory ingestion of different pharmaceutical ingredients masking odors and unpleasant flavors

At Softigel, we offer much more than traditional softgels, including everything from a single unit dosage form, to multiple delivery systems in a single dose. Softgels are an effective delivery system for oral drugs, especially those with low solubility and/or permeability (BCS Classes II, III and IV).     Softigel´s deep formulation and manufacturing expertise iin softgel advanced technologies, offers the following advantages

Key Softgel characteristics
•Enhanced bioavailability of active ingredients  •Attractive physical appearance 
 •Greater stability 
 •Extended shelf life 
 •Masks unpleasant odors and flavors 
 •Consumer preferred dosage form (easier to swallow than traditional dosage forms)

Innovative softgel technologies for otc, rx and nutraceutical products that can maximize your brands´ and market potential. Ideation, expertise and quality come together.  Our experience developing hundreds of softgel products is supported by a comprehensive selection of advanced softgel technologies and the ability to develop, manufacture and supply them efficiently.

Explore the series of Learning Labs at CPhI North America across several product innovation categories in which thought leaders at our exhibitors showcase their extensive expertise in all areas of the pharma supply chain, offering industry insights across drug manufacturing, outsourcing, pharma ingredients, drug delivery and packaging.

Meet our vegetarian softgel technology, Versagel™️, a versatile option for the encapsulation of high viscous, semisolid or high pH fill contents. This is a platform that has been built at Procaps from different standpoints such as: Formulation, R&D, Process, Product and Experience.

As consumers become increasingly knowledgeable about the different delivery formats available, so they continue to demand more from both pharmaceutical and nutraceutical products. As a result, the race to create the next ‘super pill’ has intensified. One of the leading contenders in this race is Unigel softgel.

Harnessing the power of effective 3D experiences,  Softigel by Procaps launches The Hubble tour,  a virtual booth platform that offers a unique proposition to have interactions just like real-life events, where attendees can walk through its interactive stations, view spaces in 360°, Find and click hotspots, visualize and discover products in 3d that are customizable to any customer’s needs, download rich content, chat, and view interactive videos. An amazing online experience in Full high definition!

The Hubble tour is a new way for companies to have a deep understanding of what we do as an integrated CDMO, to explore new product ideas in novel dosage forms, learn how our expertise & technologies can meet brands and company’s needs, chat with our team of experts in real-time, share content to other colleagues, and much more!

With advances in technology transforming drug delivery systems, these are exciting times for the pharmaceutical industry. Not only are companies finding innovative ways to optimise manufacturing processes, but more importantly, new technologies are being developed that improve the lives of patients.

Unigel™️,  is a first-to-market technology designed to combine multiple API formulations in one single soft gelatin capsule, offering multi-phase therapies, improving bioavailability, reducing manufacturing costs, and achieving superior adherence to different therapies. Unigel™️ technology provides various forms for fixed-dose combinations, such as a softgel in a softgel, a tablet in a softgel, granules in a softgel, or any combination to address challenges of multiactive formulation, offering unique prescription, otc and otx products.

Highly stable and offering a long shelf life, soft gelatin (softgel) capsules have gained popularity as an alternative supplement delivery system to oils and pills. They can also help manufacturers enhance the bioavailability of active pharmaceutical ingredients (APIs).

The Softgel Capsule is a superior delivery system with wide-ranging applications. They are a solid dosage form composed of two gelatin films that contain semisolid or liquid APIs protected by an external, hermetically sealed cover. They ensure high precision dosage by achieving homogeneity of ingredients.

Carol Helena Aguilar Rodríguez – Pharmaceutical Chemist, Procaps SA

Carolina Quintero Ochoa – PhD Polymer Science and Engineering, Procaps SA

Discover how our passion for innovation turns into revolutionary technologies that are ideal for consumers health and nutrition. Unigel™ is the only technology available for fixed dose combinations, that allows multiple ingredients to co-exist in one single dose

If you’re looking for news, product information and market trends from leading pharma companies, the CPhI-Online.com Company Showcases are a great resource for buyers who want to stay up to date, browse product portfolios and find the right partner. 

The Company Showcase profiles offer a library of free to access, downloadable content, including videos and webinars, reports, whitepapers and product brochures, from the Pharma suppliers and service providers you’d look to meet at our events.

Dive into the next generation of softgel technologies. We are your integrated CDMO

Appearing in the September 2020 edition of Tablets & Capsules, this article summarizes a method for rapid and accurate determination of API concentration in the fill of soft gelatin capsules while little or no sample preparation. Applying chemometric models to near-infrared spectrum data allows scientists to predict the API content in samples from the manufacturing process and the final product.

A key factor in our market success is having a R&D team working continuously on the development of formulas and pharmaceutical technologies. Our experience is at your disposal. Contact us and get to know us more! 

The present is an overview of the state-of-the-art for vegetarian soft capsules in terms of materials (sourcing and demand), applications, processing, products and a general insight of the current state of materials and technology of these gelatin alternatives.

Softigel® by Procaps is a leading provider of Contract Development and Manufacturing services in softgel advanced technologies for the global pharmaceutical and nutraceutical industry. Through our extensive capabilities and deep expertise in product development and softgel manufacturing, we help different companies bring innovative products to their markets faster, offering their patients and consumers an exceptional experience, high preference and superior adherence to different therapies.  Our advanced delivery technologies, including Softgel and related technologies, our proven formulation, manufacturing and regulatory expertise, has enabled us to become an integrated CDMO (iCDMO), giving customers full-service, turnkey solutions in prescription drugs, OTC and dietary supplements across both development and delivery.  

 Vitamin D contributes to the maintenance of normal bones and muscle function and helps to reduce the risk of falling associated with postural instability and muscle weakness

Discover our Chewable Softgel capsules platform Chewgels, a solution and line extension to existing or new products. With new ingredients, special shapes and flavors, we can offer our customers a range of formulations for different therapeutic lines.

Gummy supplements alone have gained the most market share in relation to others non-pill formats doubling in size over the last five years

This article is aimed to offer a general review of the fixed dose combinations (FDC), the manufacturing technologies and their applications, benefits and setbacks as well as a case study to illustrate the product concept based on the new technological platform of Unigel®️ for FDCs in soft gelatin capsules

Learn more on our unigel technology, platform for multi-purpose, multi-dose therapies in fixed dose combinations in softgels. Ready-to-market formulas available. 

One of the most frequent issues in product development of soft gelatin capsules is dissolution performance. Gelatin is a protein containing terminal reactive amino o carboxylic groups which proceed to crosslinking reactions, leading to the formation of insoluble high molecular weight chains that decrease or limit the release of the fill content of the capsules to the dissolution media. The progress of this reaction will depend on the content of high molecular weight chains, the content of free groups to react in gelatin or the reactive impurities in excipients. In product formulation, some properties of the gelatin such as the gelatin type and the molecular weight have been identified to determine the dissolution of the product. In regards to the gelatin formulation, some relevant variables are the type and content of plasticizer.

Get a closer look at how our team of experts identify market opportunities from an early stage and are constantly thinking of ways to revolutionize the pharmaceutical industry:

The present is an overview of the state-of-the-art for vegetarian soft capsules in terms of materials (sourcing and demand), applications, processing, products and a general insight of the current state of materials and technology of these gelatin alternatives.

Selecting the appropriate dosage form in the development and manufacturing of Cannabis-based products plays an important role in the success of the drug product because the dosage form selected should be able to protect the drug substance during all the shell life and facilitate its handling and administration to patients and consumers.

At Fun-trition we are focused on offering a complete experience in every bite of our delicious gummies. From Plant-based technologies to guilt-free, sugar-free gummy formulations we understand that good nutrition doesn't have to be boring.

Fixed-dose combinations are the preferred approach to simplify the management of chronic diseases such as HIV, asthma, diabetes, lipid regulation, and hypertension by reducing the number of dosage intake and improving efficacy as well as offering a more cost-effective therapeutic option to monotherapy. However, there are various challenges in the fabrication of multi-layered tablets that need to be considered to achieve optimal manufacturing at an industrial scale. This whitepaper from Procaps provides an overview of recent academic works regarding the implementation of how Additive Manufacturing (3D Printing) technologies have emerged to develop pharmaceutical products, particularly the design and manufacturing of dose combination products for chronic patients.

The Pharma industry is shifting from volume to value – addressing smaller patient populations and rare diseases. 3D printing (3DP) technologies have a transformational role to play. However, 3DP comprises an array of different additive manufacturing technologies of which only some can be adapted to the use in pharmaceutics. This session will discuss the use of 3D printing in a hospital setting to prepare personalised therapies for paediatric patients. For the first time, 3D printing offers a feasible, rapid and automated approach to prepare oral tailored-dose therapies for patient improving safety and adherence to the treatment. Podcast aired as part of the CPhI Festival of Pharma

More than 4 decades developing medical solutions for the world.

Procaps is a developer of pharmaceutical and nutraceutical solutions, medicines, and hospital supplies that reach more than 50 countries in all five continents. Procaps has a direct presence in 13 countries in Latin America and, as of December 31, 2020, had more than 4,700 collaborators working under a sustainable model. Procaps develops, manufactures, and markets over-the-counter (OTC) and prescription drugs, nutritional supplements and high-potency clinical solutions. 

As an integrated CDMO in Softgel Technologies, we offer end-to-end solutions from development across delivery.We value ourselves as a business partner that can be flexible enough to work with your needs and deliver innovative and specialty products that fit your patients and market needs. Meet with us

At Softigel® by Procaps, we are continuously working on bringing you unique product features to differentiate your brand. Breakthrough technologies to reach new markets.  

 Through our extensive capabilities and deep expertise in product development and softgel manufacturing, we help different companies bring innovative products to their markets faster, offering their patients and consumers an exceptional experience, high preference, and superior adherence to different therapies.

Selecting the right delivery format for your next product launch is not an easy decision, essentially it should depend on several factors such as dosage, formulation, absorption, quality, but have you thought about consumer preference and experience when choosing the format for your next big launch? Which formats are today providing enjoyable and consumer experiences, being tasteful, convenient, and delivering the required nutrition consumers are looking for?

Procaps counts with Deep knowledge and extensive experience in the Development and manufacturing of complex hormone therapy drugs, supported by our advanced softgel technologies. Learn more

This webinar originally aired as part of CPhI Discover - 17-28 May 2021 While plant-based diets continue to grow in popularity, the desire to live and act more sustainably and healthfully is on the rise. With our Vegetarian Softgel Technology, Versagel™, companies can now offer their patients and consumers Non-GMO, plant-based softgel products as an optimal solution for their latest demands without losing the versatility and benefits of regular softgel capsules. Changing to a plant-based alternative should not affect overall product performance and quality. Versagel™ offers not only great appearance, but an overall competitive edge, the cornerstone for your next big project. Join us!

This webinar originally aired as part of CPhI Discover - 17-28 May 2021 Latin America is a diverse market with a huge population that has commanded the attention of pharma companies as one to watch. This session will explore how the potential of this dynamic market can be tapped into. Overview of the current market opportunities & challenges across key markets - Brazil, Mexico, Chile, Colombia, Argentina and Central America. Key therapy areas & most promising markets Innovation landscape Potential drivers to the increasing internationalization of the LatAm Pharma Market What has been the impact of the pandemic on the Latam pharmaceutical market?