News
1 Oct 2021
Rigid or Flexible isolator?Flexible or Rigid Containment?There are many options today but HOW TO CHOOSE?
FOR CONTAINMENT OF POWDERS
Favor rigid containment when:
- Material is Highly Potent (1 µg/m3 or less, OEB5 & 6)
- Frequent usage
- High resistance needed to aggressive materials, pressure, solvents, etc
- Process equipment needs to be integrated
- Capital is available
- Material is hot highly potent (OEB4, 1 µg/m3 maximum)
- Low usage
- Faster lead time is needed
- Staff has high technical skills to conduct delicate procedures
- Limited capital available and consumables budget is not an issue
- The isolator must be resistant to temperature, pressure, VHP
- Flexible films have limitations
- VHP generator must be integrated
- The preferred choice is a rigid isolator (with integrated VHP generator)
- Flexible solutions are well established for transfers
- The variety of flexible transfer solutions has grown a lot the last 10 years
- Small to medium quantities are a good fit for flexible solutions
- Larger quantities and high usage applications are better fit for rigid solutions
- Rigid solutions like RTPs are preferred for tools & glassware transfer
Here’s a quick guide:
Mentioned Companies
FPS Food and Pharma Systems S.r.l.
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