SAM-e has been studied extensively since its chemical structure was first described in 1952 by Dr. Cantoni. Decades of research on the biochemical and molecular roles of SAM-e in cellular metabolism have provided an extensive foundation for its therapeutic use in clinical studies, including those on depression, dementia, liver disease, joint health an osteoarthritis.
SAM-e has been available as a dietary supplement in the US since 1999, but it has been used as a prescription drug in Italy since 1979, in Spain since 1985, and in Germany since 1989 and in several other countries outside EU as injectable and oral formulations.
SAM-e is available in dried mix form, powder form, granular form and tablet form. SAM-e powder is suitable for nutritional application in the form of disulphate ptoluensulfonate salt. It contains more than 75% of (S,S) isomer, recognized as the effective bioavailable form of the ingredient, and is totally obtained through a biofermentation process in a pharmaceutical manufacturing operations. Grade: Oral. Packing size: 10 kg - 25 kg, in LDPE bags. (S,S) Isomer: Greater than 75%. Certifications: Kosher, KOF-K. SAM-e Granular is a formulated bulk powder consisting of coated granules containing S-Adenosyl-L-Methinonine (SAM-e). SAM-e Granular is suitable for human and animal consumption and finds its best application when dosed in capsules and sachets. Grade: Oral. Packing size: 1 Kg - 5 Kg - 25 Kg, in LDPE bags. High Dosage formulation: SAM-e ion assay greater than 38%, Low Dosage formulation: SAM-e ion assay greater than 32%. SAM-e Coated tablets are available with conventional enteric-coated technologies in different dosages and combinations. Dosages: 50, 100, 200 and 400 mg active.
|Categories||APIs (Active Pharmaceutical Ingredients)|
|Sales markets||Western Europe; Eastern Europe; Middle East; Asia; Australia; North America; Africa; Central/South America|
|Selling Points||Brand Name; Experienced Technicians; Green Product; Guarantee/Warranty; International Approvals/Standards; Packaging; Place of Origin; Price; Product Features; Product Performance; Prompt Delivery; Quality Service; Reputation; Small Orders Accepted|
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