Samyang Biopharm USA in-licenses Talix Therapeutics’ first-in-class compound

Samyang Biopharm USA has licensed in Belgium’s Talix Therapeutics’ first-in-class immuno-oncology compound for global rights.

The anti-CD96 antibody is a first-in-class compound that is currently in preclinical phase. Samyang and Talix will jointly run the preclinical trials, and depending on the result, will carry out global clinical trials.Antibodies to CD96 have been reported to protect mice from tumors by activating T cells. In vivo studies, or studies done in living organisms, have reportedly shown evidence that such antibodies can synergize with PD-1 checkpoint blocking molecules that allows T cells to kill tumor cells.Samyang’s collaboration with Talix is the second partnership disclosed by the company in recent weeks. On Dec. 2, Samyang announced an exclusive global license-in of US-based CanCure’s first-in-class immune stimulatory monoclonal antibody targeting soluble MHC class 1 chain-related protein, a byproduct of tumor cells.