SEMI PILOT LABORATORY

ADL is wholly focused on our customers’ commercial success. One key point in the biotech industry is to design a robust process that can be efficiently transferred and scaled up for production at different sizes. ADL´s flexible facilities with state-of-the-art equipment enable us to provide the required support from the earliest stages of the development process.

• Fermenters:

2 x 5 L (Biostat B, Sartorius)
3 x 30 L (Biostat C Plus, Sartorious)
2 x 65 L (BioFlo 610, Eppendorf)

• Head plate ports:

Acid, Alkali, Antifoam plus 4-5 additional ports

• Vessel side ports:

pH, Temperature, dO2, Biomass

• Temperature

15 to 135º C +/- 0.5º C

• pH

PID control system. Automatic addition

• Aeration

PID control system.
● Surface (top)
● Sparger (bottom)

• Dissolved oxygen

Regulated by: ● Air supply
● Head pressure
● Agitation speed

Cascade control

• Agitation

Rushton turbines (x3)
Speed controlled by motor with frequency inverter

• Volume & foam

Filling volume (Weighting cell)
Maximum filling volume (Level probe)
Foam (Level probe). Antifoam automated addition.
Mass flow meters (Nutrients addition)

• Automation

PLC control (touch screen)
Automatic operations include:
● Pressure test
● SIP
● Volumes transfer (media, nutrients, broth)

• Acquisition & data storage

SCADA monitoring system