SERVATOR H

SERVATOR H
Product Description

The device is used for the preservation of

organs with venous or arterial segments

for the transplant (heart, kidney, liver, lung,

pancreas).

The device can be used only by medical staff

properly trained to its use, in accordance with

established operating protocols.

AVAILABLE IN THE FOLLOWING

S.A.L.F SpA

  • IT
  • 2015
    On CPhI since
Manufacturer/Innovator

S.A.L.F SpA

  • IT
  • 2015
    On CPhI since
Manufacturer/Innovator

More Products from S.A.L.F SpA

  • METOCLOPRAMIDE S.A.L.F. 10mg/2ml

    Product METOCLOPRAMIDE S.A.L.F. 10mg/2ml

    La metoclopramide stimola e coordina la motilità del tratto superiore dell’apparato gastroenterico, senza modificare la secrezione gastrica, pancreatica e biliare.Il suo meccanismo d’azione è complesso, essendo il farmaco antagonista competitivo dei recettori D1 e D2 (dopamina) e dei recettori 5-HT3 (serotonina), nonché agonista aspecifico dei recettori 5-HT4 coinvolti nella stimolazione dei neuroni colinergici enterici. Ha quindi attività procinetica intestinale, indipendente dall’innervazione vagale ma abolita da atropina e altri antagonisti muscarinici.Essa determina un aumento del tono e dell’ampiezza delle contrazioni gastroduodenali e, in misura progressivamente ridotta in senso distale, un incremento coordinato dei movimenti propulsivi del digiuno, dell’ileo e del colon, con una progressione periferica del contenuto endoluminale. Aumenta ancora il tono della muscolatura del terzo medio e inferiore dell’esofago e quindi la pressione a livello dello sfintere, rilasciando nel contempo piloro e bulbo duodenale. Queste azioni si traducono in un accelerato svuotamento gastrico e in una diminuzione del reflusso dal duodeno nello stomaco e nell’esofago. Confezionamento: Metoclopramide - astuccio 5 fiale da 2ml ,10mg/2ml.

  • DOPAMINE S.A.L.F.

    Product DOPAMINE S.A.L.F.

    Dopamine acts as an agonist on specific dopamine receptors and on alpha and beta adrenergic receptors. It decreases peripheral resistance and causes mesenteric and renal vasodilation. It increases renal blood flow, glomerular filtration and urinary flow. As regards the heart, dopamine causes an increased inotropism. It differs from noradrenaline in the action on the region of the kidneys and from isoproterenol, as it does not increase the heart rate. The knowledge about cardiovascular activities of dopamine involving the activation of alpha and beta adrenergic receptors, as well as dopaminergic receptors, allows to better modulate the amine infusion, which, depending on the dose, can give effects of vasoconstriction or vasodilation, cardiac stimulation, inhibition of the increase in heart rate, diuresis, natriuresis and inhibition of aldosterone circulation. SALF is also committed to the development of two new concentrations, 200mg/5ml and 400mg/5ml.



  • SERVATOR B SALF

    Product SERVATOR B SALF


    The solution is intended for perfusion and

    hypothermic preservation of kidney, liver and

    pancreas.

    The solution kept bewween at 2° and 6° C (36°

    -43° F) is used to spray the isolated organ

    immediately before or immediately after its

    removal from the dead donor or immediately

    after its removal from the living donor.

    The solution is then left in the vessels of

    the organ during hypothermic storage and

    transport. The solution should be used for the

    cold storage of the organ and it is not suitable

    for the hypothermic preservation with a

    continuous machine perfusion.

    The device can be used only by medical staff

    properly trained to its use, in accordance with

    established operating protocols.

    AVAILABLE IN THE FOLLOWING

    PACKAGING:

    Servator B

    - Box containing 10 bags of 1000 ml.

    - Box containing 5 bags of 2000 ml.

    SHELF LIFE

    24 months

    PHYSICAL PROPERTIES:

    The solution is clear and colorless or light

    yellow.

    The solution has a calculated osmolarity

    of about 320 mosmol / l.

    pH: 7.1 to 7.5 at 20 ° C.

    The final concentration of sodium ions

    is 29 mEq / l, of potassium ions is 125 mEq / l.

  • FUROSEMIDE S.A.L.F.  250mg/25ml solution for infusion or 20mg/2ml solution for injection

    Product FUROSEMIDE S.A.L.F. 250mg/25ml solution for infusion or 20mg/2ml solution for injection

    Pharmacotherapeutic group: Diuretics with a

    major diuretic action.

    Furosemide, a synthesis saluretic agent, causes

    an increase in water and sodium elimination,

    even in cases in which the glomerular filtration

    is very limited.

    The natriuretic effect is dose-dependent,

    therefore, furosemide allows to obtain a guided

    diuresis; instead, the urinary excretion of potassium

    is significantly limited. As a result, the

    sodium-potassium ratio is extremely favorable.

    The diuretic effect following an oral administration

    begins within the first hour and lasts 4-6

    hours; by intravenous administration the effect

    occurs within few minutes and lasts about 2

    hours, while by intramuscular administration

    the effect occurs a few minutes later, but the

    duration of the action is longer.

    PACKAGING:

    Furosemide S.A.L.F. 250 mg/25 ml

    solution for injection - 5 x 25 ml

    vials A.I.C. 030671046 (Italian MA)

    Furosemide S.A.L.F. 20 mg/2 ml

    solution for injection - 5 x 2 ml

    ampoules A.I.C. 030671010 (Italian MA)

  • BLU PATENT V 2.5% S.A.L.F.  (medical device)

    Product BLU PATENT V 2.5% S.A.L.F. (medical device)


    Patent Blue V is a vital dye suitable for the marking

    of the sentinel lymph node in breast cancer

    and the intraoperative research of the sentinel

    lymph node in patients with colon cancer. It is

    also used in preoperative lymphoscintigraphy for

    sentinel lymph node biopsy in melanoma.

    PACKAGING

    Amber glass ampoule of 5 ml.

    Amber glass ampoule of 2 ml.

    Pre-filled PP syringe of 5 ml

    with protective casing

    Pre-filled PP syringe of 2 ml

    with protective casing

    CHEMICO-PHYSICAL AND 
  • CARBONE ATTIVO SALF (dispositivo medico)

    Product CARBONE ATTIVO SALF (dispositivo medico)

    This product is intended to be used for

    pre-operative detection of breast lesions, in

    particular non-palpable tumors, to allow their

    identification during surgery; it is a little diffusible

    marker, it allows you to defer the intervention

    even for several weeks and it does

    not mask the operative field. It can be used

    simultaneously with cytological sampling.

    The injection needle centering must be made

    by X-ray or ultrasound.

    The device is also used for endoscopic marking

    of lesions in the gastrointestinal tract

    (colon cancer and polyps).

    PACKAGING:

    - 2 ml pre-filled syringes

    - 5 ml pre-filled syringes

  • DIMETHYL SULFOXIDE (DMSO)

    Product DIMETHYL SULFOXIDE (DMSO)

    DMSO is a cryopreservation that prevents freezing damage to living cells and it's a commonly used for cruopreservation of bone marrow and blood componets. it is also, considered a substance with good cryoprotective characteristics for human cells, tissues, and products based on cellular tissues. DMSO has been established to be a safe and non-stem cell toxic agent. SALF DMSO is apirogenic and mycoplasma free solution. Our product complies with te highest industry standards, being a process of sterilization in the autoclave and of filtering with 0.1Um filters. SALF DMSO is classified as medical Device class III. 
  • METHYLENE BLUE 1% SALF (medical device)

    Product METHYLENE BLUE 1% SALF (medical device)

    The device is intended to be used in surgery for

    the marking of tissues and surgical findings and

    to test the tightness of urinary tract sutures and

    colorectal sutures.

    As regards tissue marking, it is suitable in particular

    for the visualization of sentinel lymph

    nodes in order to allow the removal of the potentially

    malignant lymph nodes during surgical

    procedures of the breast.

    1) MARKING OF TISSUES

    AND SURGICAL FINDINGS.

    2) CHECK OF THE TIGHTNESS

    OF URINARY TRACT SUTURES

    AND COLORECTAL SUTURES

    PACKAGING:

    5 ml PP pre-filled syringe with a protective

    overwrap.

    10 ml PP pre-filled syringe with a protective

    overwrap

  • METRONIDAZOLO SALF 500mg/100ml solution for infusion

    Product METRONIDAZOLO SALF 500mg/100ml solution for infusion

    Treatment of serious infections caused by anaerobic

    bacteria, in particular Bacteroides fragilis,

    other species of Bacteroides and other anaerobes

    on which metronidazole has a bactericidal

    effect, such as Fusobacteria, Eubacteria,

    Clostridia and gram-positive anaerobic cocci.

    Metronidazole has been used with positive

    results in septicemia, bacteremia, brain abscess,

    necrotizing pneumonia, osteomyelitis,

    puerperal fever, pelvic abscess, peritonitis and

    post-operative wounds, where one or more of

    the above-mentioned anaerobic bacteria were

    isolated.

    Prevention of post-operative infections caused

    by anaerobic bacteria, especially Bacteroides

    and anaerobic gram-positive cocci.

    Metronidazole, primarily employed for many

    years for the treatment of urogenital trichomoniasis,

    subsequently it turned out to be an active

    drug against a wide variety of anaerobic bacteria

    of clinical interest. Actually, Metronidazole has

    a bactericidal effect on obligate anaerobes, for

    which the minimum “in vitro” inhibitory concentration

    and the minimum bactericidal concentration

    of the drug are almost identical. Aerobic

    bacteria and facultative anaerobes are insensitive,

    instead.

    PACKAGING:

    - Box containing 20 x 100 ml PVCfree bags

    AIC 041491010 (Italian MA).

    - Box containing 25 x 100 ml PP bottles

  • PARACETAMOL S.A.L.F.

    Product PARACETAMOL S.A.L.F.

    Paracetamol is idicated for the short-term treatment of pain of moderate intensivity, especially following surgery adn fo the short-term tratment of fever, when the intravenous administration is justified from the clinical point of view by the urgent need of treating pain or hyperthermia and/ ord when other kinds of administration are impossible to practice. The analgesic action of paracetamol starts 5-10 minutes from start of treatment. The peak analfesic effect is obtained in 1 hours and the duration of this effect is usually 4 to 6 hours. Paracetamol reduces fecer in 30 minutes from the start of the treatment with a duration of least 6 hours. 
  • SERVATOR C

    Product SERVATOR C

    The solution is intended for the perfusion and

    hypothermic preservation of the thoracic organs

    (heart and lung) and of the abdominal organs

    (kidney, liver, pancreas) during transplantation.

    The solution at a temperature between 2° and

    8° C (36° -46° F) is used to spray the isolated

    organ immediately before or immediately after

    its removal from the dead donor or immediately

    after its removal from the living donor. The

    solution is then left in the vessels of the organ

    during hypothermic storage and transport. The

    solution should be used for the cold storage

    of the organ and it is not suitable for the

    hypothermic preservation with a continuous

    machine perfusion.

    The use of the solution at the recommended

    temperature allows to effectively cool the organ.

    The device can be used only by medical staff

    properly trained to its use, in accordance with

    established operating protocols.

    AVAILABLE IN THE FOLLOWING

    PACKAGING:

    SERVATOR C

    - Box containing 10 bags of 1000 ml.

    - Box containing 5 bags of 2000 ml.

    SHELF LIFE

    24 months

    PHYSICAL PROPERTIES:

    The solution is clear and light yellow.

    The solution is slightly hypertonic with a

    calculated osmolarity of about 242-368

    mOsmol / l, it has a low viscosity and a high

    buffer capacity.

    The solution is slightly alkaline,

    pH: 7.1 to 7.5 at 20 ° C.

  • SERVATOR P

    Product SERVATOR P

    The solution is intended for perfusion and

    hypothermic preservation of the lungs.

    Cooled between 4° and 8° C (39°-46° F), the

    solution is used to perfuse the isolated organ

    immediately after removal from the donor.

    The colloidal component dextran 40 protects in

    particular the micro vessels from the possible

    damage caused by post ischemic perfusion as

    it prevents pathological leukocyte-endothelial

    interactions.

    In addition, dextran 40 prevents oedema and

    acts against formation ofclots.

    The device should be used only by healthcare

    staff properly trained in accordance with

    established operating protocols.

    PACKAGING:

    Servator P

    - Box of 10 bags 1000 ml.

    SHELF LIFE

    24 months.

    PHYSICAL PROPERTIES:

    The solution is clear and slightly yellow.

    The solution is slightly hypertonic, with a

    calculated osmolarity of about 295 mOsmol/l.

    The solution is slightly alkaline, pH: 5.30-5.50.

    The solution may be put on the market in

    combination with a Thromethamine ampoule

    as pH modifier to 7.4.

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