• Home
  • Sever Pharma Solutions

Sever Pharma Solutions

About Sever Pharma Solutions

WE BRING YOUR PHARMACEUTICAL IDEAS TO LIFE
Sever Pharma Solutions is the committed CDMO specialized in enhancing high-potent drug product dosage forms.

Sever Pharma Solutions specializes in high-potent sustained-release delivery systems. Our services include formulation development, clinical trial material production, and commercial supply. With expertise in optimizing industrial manufacturing formulations, we effectively handle high-potent substances. Trust us for smooth clinical trials and efficient commercial production and to enhance your pharmaceutical products with our dedicated team of experts.
At Sever Pharma Solutions, we have all the services and resources to realize your pharmaceutical ideas and bring them to the market. Our manufacturing services are tailored to meet your needs, and our highly experienced analytics can solve any challenge. We develop your solutions with the end game in mind, and our regulatory experts can help you from the development phase through the registration process and with post-approval changes.

Read more Show less
Sales Markets
Show more Show less
Categories
more categories Show less
  • SE
  • 2023
    On CPHI since
  • 250 - 499
    Employees
Company types
CMO/CDMO
View company profile
Contact info
Show contact info Hide contact info
Meet us at

CPHI Milan 2024

Fiera Milano, Italy
08 Oct 2024 - 10 Oct 2024
View Exhibitor Profile

Products from Sever Pharma Solutions (4)

  • Aseptic fill and finish

    Product Aseptic fill and finish

    We offer solutions for companies that need CMO capacity concerning the aseptic filling of syringes and assembly and packaging of pre-filled syringes and auto-injectors. We will enhance your product by adding value through manufacturing if you require additional capacity or a complete technology transfer. q...
  • High-potent Dosage Forms

    Product High-potent Dosage Forms

    We have the experience, expertise, and facilities at Sever Pharma Solutions to safely work with your high-potent substances. This includes manufacturing products containing APIs that are ranked in the highest occupational exposure bands (OEB) up to and including OEB6.

    Our focus on safety starts ...
  • Hot Melt Extrusion

    Product Hot Melt Extrusion

    To successfully develop and manufacture your polymer-based delivery systems, like implants and intra-vaginal rings, we have advanced extrusion capabilities in Malmö (Sweden) and Putnam (US Connecticut). The US site is also a center of expertise for Hot Melt Extrusion (HME).

    HME improves the bioa...
  • Polymer-based delivery systems

    Product Polymer-based delivery systems

    Polymer-based dosage forms continuously administer the drug to the patient for an extended period, varying from weeks to years. These controlled-release products are very suitable for specific indications, patient populations, and drugs due to the long duration of action, avoidance of first-pass metabolism...

Sever Pharma Solutions Resources (2)

  • A COMPARISON OF SATURATED SOLUBILITY ENHANCEMENT VIA SPRAY DRYING AND HOT MELT EXTRUSION PROCESSING

    Whitepaper A COMPARISON OF SATURATED SOLUBILITY ENHANCEMENT VIA SPRAY DRYING AND HOT MELT EXTRUSION PROCESSING

    Solid solutions are similar to liquid solutions and consist of a single phase irrespective of the number of components. A solid solution of a poorly water-soluble drug dissolved in a carrier is particularly interesting in improving oral bioavailability. In a solid solution, the drug’s particle size has been reduced to its molecular dimensions resulting in a more rapid dissolution rate. By judicious selection of a carrier, the dissolution rate of the drug can be increased by up to several orders of magnitude. In a solid solution, the drug’s particle size has been reduced to its molecular dimensions resulting in a more rapid dissolution rate.

    This whitepaper compares solubility enhancement between spray drying and hot melt extrusion for a poorly soluble, new active pharmaceutical ingredient.

  • ANALYTICAL TOOLS & TECHNIQUES IN HOT MELT EXTRUSION - CASE STUDY ON PROCESS SCALE UP

    Whitepaper ANALYTICAL TOOLS & TECHNIQUES IN HOT MELT EXTRUSION - CASE STUDY ON PROCESS SCALE UP

    Hot melt extrusion has been widely used as a processing method for many purposes, including forming a solid molecular dispersion to increase the bioavailability of poorly soluble drugs. Analytical tools and techniques can significantly reduce time and improve success rates in developing hot melt extrusion formulations.

    In the scale-up phase, analytical characterization techniques ensure similar solubility enhancement occurs on larger extrusion equipment as with the lab scale equipment used for formulation development.

    In this whitepaper, you will learn more about the analytical characterization and techniques that are critical in the scale-up of melt-extruded solid dispersions to ensure similar products are produced, specifically in obtaining similar solubility-enhancing effects.