Synergy Pharmaceuticals Achieves Halfway Mark in Enrolment in Phase-II/III Plecanatide Trial
Synergy Pharmaceuticals has enrolled more than half of the patients for its phase-II/III study of plecanatide for chronic idiopathic constipation.
Synergy Pharmaceuticals has announced it has reached the halfway mark in enrolment for its phase-II/III clinical trial assessing plecanatide in patients with chronic idiopathic constipation (CIC).
Plecanatide is a type of drug called a guanylate cyclise C (GC-C) agonist and is currently being developed to treat CIC and constipation-predominant irritable bowel syndrome (IBS-C).
It is a synthetic analogue of a hormone that regulates ion and fluid transport in the gastrointestinal tract and is designed to facilitate bowel movement and reduce pain and inflammation.
A total of 440 patients have been enrolled in the ongoing phase-II/III trial since October 2011 and Syn
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