The One-stop Guide to Oligo Modification

Link Technologies Ltd, a specialist oligonucleotide reagent manufacturer, has dedicated a section of its new, freely available 2013/14 Product Guide to ‘Modification Strategies in Oligonucleotide Synthesis’.

Increasingly, modified oligos are playing an important role across a broad range of life science and clinical-based research groups and, for example, show significant promise as agents to optimise drug delivery. In the new Product Guide, Link Technologies has compiled a comprehensive resource for scientists working with modified oligonucleotides, including educational references, detailed product information, established protocols and application notes, for assured oligo synthesis and use. This go-to guide for oligonucleotide chemistry can be downloaded for free from www.linktech.co.uk

ISO 9001:2008 certified, Link Technologies offers an extensive range of modified phosphoramidites, enabling scientists to take advantage of numerous techniques and a diverse range of applications. This includes brancher phosphoramidites to facilitate the generation of branched oligos as a tool for gene expression analysis or gene correction, and hydrophobic group modifiers (cholesterol, tocopherol and palmitate) which have had recent success in aiding the cellular delivery of oligonucleotides. Application-orientated for easy use, the 2013/14 Product Guide directs scientists to the most suitable products for purpose and, with the associated tried-and-tested protocols, allows users to have confidence in the performance of their modified oligos.