Vaccine Adjuvant: Alhydrogel™

Vaccine Adjuvant: Alhydrogel™
Product Description

  • Alhydrogel is a range of aluminium hydroxide gel products which have been specifically developed for use as an adjuvant in human and veterinary vaccines
  • The gel is a suspension of boehmite-like (aluminium oxyhydroxide) hydrated nano/micron size crystals in loose aggregates
  • The products have very low conductivity due to the absence of buffering ions.
  • They have a positive charge at neutral pH and effectively adsorb negatively charged antigens
  • The primary purpose of the adjuvant in vaccines is to boost the antibody-mediated (Th2) immune response to the antigens.
  • Alhydrogel products can be combined with other adjuvant types (such as monophosphoryl lipids) to achieve a balanced Th1/Th2 immune response.
  • Alhydrogel is produced in classified clean rooms to prevent contamination, sterilised and aseptically filled in a grade A clean room.
Chemical Group
  • Aluminium oxyhydroxide
Administration Route
  • Vaccine Adjuvant
Market Application
  • Blood plasma fractionation
  • Human vaccines
  • Veterinary vaccines
Functions
  • Vaccine Adjuvant
Physical Form
  • A gel-like aqueous suspension. A supernatant forms when the product is left idle.

Croda Europe Limited

  • GB
  • 2015
    On CPHI since
  • 2
    Certificates
  • 1000 - 4999
    Employees
Company types
Manufacturer/Innovator
Primary activities
Animal Health
Custom Manufacturing/Custom Synthesis
Excipients Manufacturer
Fine Chemicals Company
Specifications
  • CAS Registry Number
    21645-51-2
  • Supplied from
    Denmark

Croda Europe Limited

  • GB
  • 2015
    On CPHI since
  • 2
    Certificates
  • 1000 - 4999
    Employees
Company types
Manufacturer/Innovator
Primary activities
Animal Health
Custom Manufacturing/Custom Synthesis
Excipients Manufacturer
Fine Chemicals Company

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Croda Europe Limited resources (6)

  • News Two new partnerships to drive sustainable delivery systems for the pharmaceutical industry

    Croda International Plc (Croda) today announced that it has signed two new partnership agreements that will help the pharmaceutical industry move towards a more sustainable supply chain for vaccine adjuvants. 
  • Brochure Addressing the challenges of vaccine formulation

    To this day, our focus has been to successfully develop, manufacture and market high-quality adjuvants for our pharmaceutical customers. This heritage makes our vaccine adjuvants unique in the industry. A heritage we are proud of. 

    Our industry-leading, Alhydrogel®, Adju-Phos® and Quil-A® are widely recognised in the vaccine industry for their unmatched track record when it comes to a proven history of safe and effective use.
  • Sponsored Content Croda: Solutions for Your High Value Drug Products

    Formulating a drug for parenteral delivery comes with its fair set of challenges. Aside from a high level of sensitivity to external factors like light and heat exposure, these large and complex drugs are prone to degradation when exposed to various chemical species.
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    This document is relevant to the following market areas

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  • Video Supporting the World's Biggest Challenges

    Smart Science to Improve Lives. For more than 75 years Croda Denmark has been dedicated to safe and effective adjuvants for use in both human and veterinary vaccines, as well as blood fractioning processes. We offer an experienced passionate team and personal interaction with comprehensive on-site advice and support anywhere in the world.
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