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17 Mar 2011

Vaccine Candidate Could Prevent Norovirus

The study supports the use of viral vector-based techniques as a new way to develop vaccines for human norovirus and other viruses that cannot grow in cell cultures.

An experimental vaccine against the human norovirus--the bug behind about 90 percent of highly contagious nonbacterial illnesses that cause diarrhea and vomiting--can generate a strong immune response in mice without appearing to cause the animals any harm, according to a new study.


Using a novel viral vector-based method to grow and deliver the vaccine--a technique that's shown promise in other agents designed to fight such infections as HIV and hepatitis C--the researchers are the first to test this vaccine design method's effectiveness against the human norovirus.


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