Vaxxas HD-MAP to deliver vaccines directly to the skin
Company awarded US$5 million grant for clinical study of measles and rubella vaccination using Vaxxas’ high-density, micro-array patch.
Biotechnology company, Vaxxas, has received a US$5 million grant from the Bill & Melinda Gates Foundation to conduct first-in-human human clinical studies using the company’s High-Density Microneedle Array Patch (HD-MAP) for measles and rubella vaccination.
The measles and rubella vaccine formulation used to coat the HD-MAP has been engineered to be stable at higher temperatures than required for needle/syringe vaccination. This improved thermal stability can reduce the cost and complexity of the cold distribution chain that is required for many conventional vaccines, enabling distribution of HD-MAP vaccines to parts of the world where refrigeration is unreliable or even nonexistent.
Professor David Durrheim, University of Newcastle and Chair of the Western Pacific Measles and Rubella Regional Verification Commission explained the need for new vaccine delivery methods that overcome the current limitations of needle and syringe vaccine delivery by skilled health professionals with reliable refrigeration is urgent.
The micro-array patches, could, according to Professor Durrheim be regarded as a potential “game-changer”.
The proprietary HD-MAP platform induces robust immune system activation by targeting relevant vaccine components to the abundant immunological cells immediately below the surface of the skin. In Vaxxas’ most recent clinical study evaluating performance using influenza vaccine, the HD-MAP using 1/6 dose induced similar immune response to full dose by needle and syringe.
Through the grant funding of the foundation, Vaxxas will optimize its HD-MAP measles and rubella vaccine in a number of important ways, including ensuring the vaccine is stable for a period at room temperature combined with a product design that will allow the vaccine to be administered by individuals with minimal to no formal medical training as may be necessary in certain countries and regions.
Related News
-
News Moderna to buy OriCiro Genomics in USD $85 million deal
Pharmaceutical company Moderna acquires genomics services company OriCiro Genomics, based in Tokyo, Japan, to boost mRNA therapeutics development and manufacturing portfolio. -
News New year, new prices: at least 350 drugs in USA to see price increases in January
Drugmakers such as Pfizer, GSK, BMS, AstraZeneca, and Sanofi are planning to raise prices for at least 350 unique drugs in the United States in early January. -
Sponsored Content 2023 Pharma Trend Outlook: Innovation, Resilience, and Pharma 4.0
Download our 2023 Pharma Trends Outlook report to discover the trends set to shape the pharmaceutical landscape in the new year, with expert opinions and insight from across the pharmaceutical value chain. -
News Strategic partnership between AstraZeneca and G42 Healthcare to increase pharmaceutical manufacturing in Abu Dhabi
A comprehensive, long-term partnership agreement between AstraZeneca and G42 Healthcare is set to enhance local drug manufacturing in Abu Dhabi, UAE, and bolster pharmaceutical manufacturing innovation within the country. -
News CordenPharma joins sustainability initiative to achieve Net Zero
The CDMO has joined the environmental initiative looking to align private sector companies with those aims upheld by the Paris Agreement to reduce global warming. -
News AstraZeneca acquires Neogene in shift into cell-based cancer therapies
AstraZeneca has recently announced that it will be acquiring the biotechnology company Neogene Therapeutics as part of it’s expansion into cell-based cancer treatments.
-
News A mRNA universal flu vaccine is in early stages of development
Researchers from the University of Pennsylvania have developed a universal flu vaccine using nanoparticle encapsulated mRNA. -
News Biovac partnership to increase African vaccine manufacturing capabilities
South African biopharma company Biovac signs a partnership deal with the International Vaccine Institute to develop and manufacture an oral cholera vaccine for both the African and global market.
Position your company at the heart of the global Pharma industry with a CPHI Online membership
-
Your products and solutions visible to thousands of visitors within the largest Pharma marketplace
-
Generate high-quality, engaged leads for your business, all year round
-
Promote your business as the industry’s thought-leader by hosting your reports, brochures and videos within your profile
-
Your company’s profile boosted at all participating CPHI events
-
An easy-to-use platform with a detailed dashboard showing your leads and performance