Xencor Launches XmAb5871 Phase 1 Study
XmAb5871 uses a novel dual-targeted approach to potently suppress autoimmune disorders that may avoid some of the side effects seen with other therapeutic antibodies that modulate immune response.
US biopharmaceutical firm Xencor, Inc. announced last week the initiation of a Phase 1 clinical trial of XmAb(R)5871, the company's therapeutic antibody for the treatment of autoimmune diseases.
XmAb5871 uses a novel dual-targeted approach to potently suppress autoimmune disorders that may avoid some of the side effects seen with other therapeutic antibodies that modulate immune response. The advancement of XmAb5871 into clinical stage testing demonstrates the broad potential of Xencor's antibody engineering technology in immune and inflammatory diseases in addition to oncology.
The endpoints of the Phase 1 study are safety, pharmacokinetics and a number of biomarkers of immunomodulatory drug activity.
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