Xiamen Amoytop Biotech Co. Ltd

Filgrastim is a recombinant human granulocyte colony stimulating factor (rHuG-CSF), produced by recombinant DNA technology using E.coli. It is a 175 amino acid protein, non-glycosylated, and has a molecular weight of approximately 18.8kD. The protein has an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal methionine necessary for expression in E. coli.brhrbrAppearance Properties: Sterile, clear and colorless liquid for injection in vial

Specifications: 75µg, 100µg, 150µg, 200µg, 300µg and 480µg

Indications:
1. Neutropenia resulting from cancer chemotherapy.
2. Neutrophil decrease after bone marrow transplantation.
3. Neutropenia caused by Myelodysplastic syndrome, neutropenia caused by aplastic anemia; congenital neutropenia, idiopathic neutropenia, Myelodysplastic syndrome with neutropenia and Periodic neutropenia.
4. Patients undergoing peripheral blood progenitor cell collection and therapy.

Molgramostim is a recombinant human granulocyte macrophage colony stimulating factor (rHuGM-CSF), produced by recombinant DNA technology using E.coli. It is a 127 amino acid protein, non-glycosylated, and has a molecular weight of approximately 14.5kD.brhrbrAppearance Properties: Sterile and white lyophilized powder to be reconstituted with a diluent (Sterile Water for Injection) for injection, presented in vials.

Specifications: 50µg/vial, 75µg/vial, 100µg/vial, 150µg/vial, 300µg/vial and 400µg/vial.

Indications:
1. In patients receiving myelosuppressive therapy cancer chemotherapy to reduce the severity of neutropenia, thereby reducing the risk of infection and allowing better adherence to the chemotherapeutic regimen;

2. In patients undergoing autologous or syngeneic bone marrow transplantation to accelerate myeloid recovery (Molgramostim does not improve overall survival or increase time to relapse);

Dosage form: Sterile, preservative-free, clear injectable solution for s.c. administration

Strength and package: 180μg (0.66MU)/0.5ml in a single use vial or prefilled syringe

Shelf life and storage: 36 months at 2ºC - 8ºC, protect from light

Indication: Chronic hepatitis B & C

Oprelvekin is a recombinant human interleukin 11, produced by recombinant DNA technology using E.coli. It has a molecular weight of approximately 19.0kD, non-glycosylated. The polypeptide is 177 amino acids and differs from the 178 amino acid length of native IL-11 only in lacking the amino-terminal protein residue, this alteration has not resulted in measurable differences in bioactivity either in vitro or in vivo.brhrbrAppearance Properties: Sterile and white lyophilized powder to be reconstituted with a diluent (Sterile Water for Injection) for injection, presented in vials.

Specifications: 1mg/vial, 1.5mg/vial, 2mg/vial, 3mg/vial and 5mg/vial

Indications:
Oprelvekin is indicated for severe thrombocytopenia with degree III and IV induced by chemotherapy to solid tumor and to non-marrow leukemia. It could be administered together with rHuG-CSF to treat patients with leucopenia.

Xiamen Amoytop Biotech Co Ltd provides wide range of products which includes recombinant enterokinase. It belongs to reagents category. It is the catalytic subunit of bovine enterokinase, which is expressed by the yeast pchia pastoris and purified to yield a high enzyme activity preparation. Rek recognizes the sequence asp-asp-asp-asp-lys and cleaves the peptide bond after the lysine residue. Contact us for more information.

Xiamen Amoytop Biotech Co Ltd provides wide range of products which includes recombinant human gm-csf. It belongs to reagents category. It is a single, non-glycosylated, polypeptide chain containing 127 amino acids, two pairs of disulfide bonds and having a molecular mass of approximately 14.5kd. Contact us for more information.

Xiamen Amoytop Biotech Co Ltd provides wide range of products which includes recombinant human stem cell factor. It belongs to reagents category. Contact us for more information.

Xiamen Amoytop Biotech Co Ltd provides wide range of products which includes recombinant human tnf-alfa. It belongs to reagents category. Contact us for more information.

Xiamen Amoytop Biotech Co Ltd provides wide range of products which includes recombinant human interleukin 4. It belongs to reagents category. Contact us for more information.

Xiamen Amoytop Biotech Co Ltd provides wide range of products which includes recombinant human interferon alfa-2a. It belongs to reagents category. It is a single, non-glycosylated, polypeptide chain containing 165 amino acids, two pairs of disulfide bonds and having a molecular mass of approximately 19.2kd. Contact us for more information.

Xiamen Amoytop Biotech Co Ltd provides wide range of products which includes recombinant human interferon alfa-2b. It belongs to reagents category. It is a single, non-glycosylated, polypeptide chain containing 165 amino acids, two pairs of disulfide bonds and having a molecular mass of approximately 19.3kd. Contact us for more information.

Xiamen Amoytop Biotech Co Ltd provides wide range of products which includes recombinant human interferon gamma. It belongs to reagents category. It is a non-covalent dimer non-glycosylated, containing 140 amino acids, and having a molecular mass of approximately 16.5kd. Contact us for more information.