Amylin and Takeda End Development of Obesity Treatment
The firms say the decision to discontinue the program is based on a commercial reassessment, which included the evaluation of a revised development plan.
San Diego-based biopharmaceutical company Amylin Pharmaceuticals and its Japanese partner Takeda Pharmaceutical have decided to end development of the Phase II-stage obesity therapy candidate pramlintide/metreleptin.
The firms claim that the decision to discontinue the program is based on a commercial reassessment, which included the evaluation of a revised development plan. However, in March they suspended an ongoing Phase II trial evaluating pramlintide/metreleptin due to what was described as an antibody-related laboratory finding associated with metreleptin treatment in two patients who participated in a previously completed obesity clinical study.
Amylin and Takeda say they will continue to evaluate other assets for the potential treatment of obesity as part of their ongoing coll
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