Bavarian Nordic secures contract award for supply of freeze-dried Imvamune smallpox vaccine to the US government

4 Oct 2017

Initial base award secures additional Imvamune bulk contract of USD 100 million.

Bavarian Nordic has announced the award of a sole source contract from the Biomedical Advanced Research and Development Authority (BARDA), part of the Office of the Assistant Secretary for Preparedness and Response at the US Department of Health and Human Services (HHS), for the procurement of freeze-dried Imvamune smallpox vaccine. The potential value of the initial base and optional awards is in excess of USD 539 million.

Bavarian Nordic secures contract award for supply of freeze-dried Imvamune smallpox vaccine to the US government
Paul Chaplin, President and CEO of Bavarian Nordic.

The initial award in the contract calls for the manufacturing and storage of USD 100 million of IMVAMUNE bulk. This is the third such award to manufacture vaccine bulk; with the two prior orders totaling USD 233 million. The initial options in the contract are divided between two distinct areas, the first of which is the filling and freeze-drying of IMVAMUNE from the three bulk awards, with total potential value of USD 299 million. The second part of the contract contains provisions for clinical development, regulatory commitments, and parts of the establishment and validation of fill/finish activities, with potential value of up to USD 140 million. The award also contains options to acquire additional vaccine bulk and/or freeze-dried doses of IMVAMUNE in the future.

To ensure the production capacity to secure the future IMVAMUNE stockpile at the U.S. Strategic National Stockpile, Bavarian Nordic will invest approximately USD 75 million over the coming years in the construction of a fill/finish manufacturing line at its facility in Denmark. As part of Bavarian Nordic's long-standing partnership with BARDA, a potential optional award of up to USD 33 million (part of the USD 140 million mentioned above) is dedicated to process transfer, and validation of the new manufacturing line. This strategic investment will allow Bavarian Nordic to recognize the full value chain of the manufacturing process, to maintain control of the product cycle throughout, and the potential to provide these services to third parties in the future.

"We are proud to be part of a long-standing and successful partnership with BARDA and this latest contract starts a new chapter, as we supply an improved formulation of our vaccine as part of the US government commitment to protect the nation from a smallpox outbreak " said Paul Chaplin, President and CEO of Bavarian Nordic. "Our latest strategic investment that will expand our manufacturing capacities will add value, not only to our partnerships, but also to our proprietary pipeline."

Read More

Related tags

Market News

Related news

Aptar Pharma to showcase an industry first

Aptar Pharma to showcase an industry first

12 Sep 2018

PureHale is a new portable drug delivery device designed for upper respiratory care.

Read more 
Novartis to divest the Sandoz US dermatology business and generic US oral solids portfolio

Novartis to divest the Sandoz US dermatology business and generic US oral solids portfolio

11 Sep 2018

The Sandoz US portfolios to be sold to Aurobindo include approximately 300 products, as well as additional development projects.

Read more 
New SGS biopharmaceutical testing capabilities in Illinois

New SGS biopharmaceutical testing capabilities in Illinois

11 Sep 2018

The new services will focus on quality control analysis and stability testing of biopharmaceuticals.

Read more 
Exciting skincare to protect against blue light emitted by phones and devices

Exciting skincare to protect against blue light emitted by phones and devices

10 Sep 2018

Novel, dual-acting product revitalizes and protects skin against blue light and environmental aggressors around the clock.

Read more 
24/7 life science manufacturing IT service launches

24/7 life science manufacturing IT service launches

7 Sep 2018

Faster GMP incident response and resolution times when manufacturing IT applications fail or are not running to their optimum capacity.

Read more 
Catalent signs commercial supply agreement for Aucta Pharmaceuticals' vigabatrin

Catalent signs commercial supply agreement for Aucta Pharmaceuticals' vigabatrin

6 Sep 2018

Novel dosage form employs Catalent’s proprietary stick pack dosage form.

Read more 
Sartorius and Repligen partner to introduce next-generation perfusion-enabled bioreactors

Sartorius and Repligen partner to introduce next-generation perfusion-enabled bioreactors

5 Sep 2018

Customers to benefit from simplified, scalable solutions for intensified cell culture.

Read more 
Boehringer Ingelheim to build new tablet manufacturing facility

Boehringer Ingelheim to build new tablet manufacturing facility

4 Sep 2018

Facility to manufacture innovative drugs for worldwide market launches and technologically advanced production.

Read more 
Plasticell wins military contract to develop regenerative medicines for the battlefield

Plasticell wins military contract to develop regenerative medicines for the battlefield

4 Sep 2018

Company to use its combinatorial stem cell screening platform to develop technologies for the conversion of pluripotent stem cells into platelets.

Read more 
Bio processing and manufacturing league table ranks US top and China bottom

Bio processing and manufacturing league table ranks US top and China bottom

3 Sep 2018

US, Germany and Japan revealed as tier one nations in all categories with Sweden ranking the best of the rest.

Read more