Copley Scientific Showcases New Products for Smarter Inhaled Product Testing at DDL 24

New products for smarter, more representative inhaled product testing will be on display at the Copley Scientific stand at Drug Delivery to the Lungs 24 (DDL 24, 11–13 December 2013, Edinburgh International Conference Centre, Scotland).

The latest additions to the Copley Scientific range help to make inhaled testing more efficient and improve the in vivo relevance of in vitro test methods. Centre stage will be the new Child Alberta Idealised Throat which is used to gather test data that is of direct relevance to paediatric patients.

All orally inhaled products (OIPs) are characterised in terms of aerodynamic particle size distribution to infer information about where in the lung they may deposit. The highly successful Alberta Idealised Throat (AIT) was developed as an alternative to the standard USP induction port, which is used to interface the product with the test equipment during this measurement process. With a standardised, highly reproducible, human-like geometry, the AIT has been shown to more accurately simulate the deposition of OIPs in the upper respiratory tract, relative to the USP induction port, making testing more representative of in vivo behaviour. The new Child Alberta Throat is based on child and infant throat geometry, and extends this facility for more representative testing to those developing products for paediatric patient groups.

Also on display will be the new TPK-R critical flow controller, the BAC 2000, breath actuation controller and a new breathing simulator model, the BRS 1100. A reverse version of the TPK critical flow controller the TPK-R has recently been launched to improve the ergonomics of test set-up for dry powder inhaler (DPI) testing. The BAC 2000 allows for the testing of breath actuated MDIs and together with the BRS 1100, simplify nebuliser testing in accordance with the latest regulatory guidance. In combination, they also provide an efficient solution for characterising MDIs with spacers and valved holding chambers, in line with the strategy outlined in a recently published USP stimuli to the revision process.