Dara Begins Study of Diabetes Drug
The study is designed to determine the safety and pharmacokinetics of multiple ascending oral doses of DB959 in men and women.
Dara BioSciences has launched a Phase Ib clinical study of DB959, its peroxisome proliferator-activated receptor delta / gamma agonist for the treatment of type 2 diabetes. Results are expected to be published during the third quarter of 2011.
DB959 affects certain nuclear receptors that regulate the genes involved in controlling blood sugar levels and certain lipids. The study is designed to determine the safety and pharmacokinetics of multiple ascending oral doses of DB959 in men and women.
The results of a Phase Ia study demonstrated a promising safety profile and pharmacokinetic profile that supports a once-a-day oral dose.
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