Exagen and Medco Start Program to Aid in Personalized RA Treatment
The study aims to understand how methotrexate is being absorbed, retained, and metabolized by a patient.
Exagen Diagnostics and Medco Research Institute have started a pilot program to assess the ability of the former’s test to optimize low-dose methotrexate (MTX) therapy for rheumatoid arthritis (RA). The study aims to understand how MTX is being absorbed, retained, and metabolized by a patient.
Exagen's lab test, called Avise PG, will be used to measure whether patients are receiving an appropriate dose of MTX. Avise PG measures MTX polyglutamate levels, the active metabolites of MTX. Medco Research Institute will work with Medco clients to recruit patients to take part in the pilot program.
When a volunteer receives an initial MTX prescription for RA, Medco will provide the prescribing physician with the Avise PG test, and patients will be alerted that a blood-
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