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FUROSEMIDE S.A.L.F. 250mg/25ml solution for infusion or 20mg/2ml solution for injection
Pharmacotherapeutic group: Diuretics
major diuretic action.
Furosemide, a synthesis saluretic agent, causes
an increase in water and sodium elimination,
even in cases in which the glomerular filtration
is very limited.
The natriuretic effect is dose-dependent,
therefore, furosemide allows to obtain a guided
diuresis; instead, the urinary excretion of potassium
is significantly limited. As a result, the
sodium-potassium ratio is extremely favorable.
The diuretic effect following an oral administration
begins within the first hour and lasts 4-6
hours; by intravenous administration the effect
occurs within few minutes and lasts about 2
hours, while by intramuscular administration
the effect occurs a few minutes later, but the
duration of the action is longer.
Furosemide S.A.L.F. 250 mg/25 ml
solution for injection - 5 x 25 ml
vials A.I.C. 030671046 (Italian MA)
Furosemide S.A.L.F. 20 mg/2 ml
solution for injection - 5 x 2 ml
ampoules A.I.C. 030671010 (Italian MA)
2015On CPhI since
2015On CPhI since
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Dopamine acts as an agonist on specific dopamine receptors and on alpha and beta adrenergic receptors. It decreases peripheral resistance and causes mesenteric and renal vasodilation. It increases renal blood flow, glomerular filtration and urinary flow. As regards the heart, dopamine causes an increased inotropism. It differs from noradrenaline in the action on the region of the kidneys and from isoproterenol, as it does not increase the heart rate. The knowledge about cardiovascular activities of dopamine involving the activation of alpha and beta adrenergic receptors, as well as dopaminergic receptors, allows to better modulate the amine infusion, which, depending on the dose, can give effects of vasoconstriction or vasodilation, cardiac stimulation, inhibition of the increase in heart rate, diuresis, natriuresis and inhibition of aldosterone circulation. SALF is also committed to the development of two new concentrations, 200mg/5ml and 400mg/5ml.
The solution is intended for perfusion and
hypothermic preservation of kidney, liver and
The solution kept bewween at 2° and 6° C (36°
-43° F) is used to spray the isolated organ
immediately before or immediately after its
removal from the dead donor or immediately
after its removal from the living donor.
The solution is then left in the vessels of
the organ during hypothermic storage and
transport. The solution should be used for the
cold storage of the organ and it is not suitable
for the hypothermic preservation with a
continuous machine perfusion.
The device can be used only by medical staff
properly trained to its use, in accordance with
established operating protocols.
AVAILABLE IN THE FOLLOWING
- Box containing 10 bags of 1000 ml.
- Box containing 5 bags of 2000 ml.
The solution is clear and colorless or light
The solution has a calculated osmolarity
of about 320 mosmol / l.
pH: 7.1 to 7.5 at 20 ° C.
The final concentration of sodium ions
is 29 mEq / l, of potassium ions is 125 mEq / l.
Patent Blue V is a vital dye suitable for the marking
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sentinel lymph node biopsy in melanoma.
Amber glass ampoule of 5 ml.
Amber glass ampoule of 2 ml.
Pre-filled PP syringe of 5 ml
with protective casing
Pre-filled PP syringe of 2 ml
with protective casing
S.A.L.F SpA resources
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